中国实用医药
中國實用醫藥
중국실용의약
China Practical Medical
2015年
30期
8-9
,共2页
李宏%程新华%任重庆%周东良%李佳琦
李宏%程新華%任重慶%週東良%李佳琦
리굉%정신화%임중경%주동량%리가기
低分子肝素%患肢%静脉注射%皮下注射%下肢深静脉血栓形成
低分子肝素%患肢%靜脈註射%皮下註射%下肢深靜脈血栓形成
저분자간소%환지%정맥주사%피하주사%하지심정맥혈전형성
Low molecular weight heparin%Affected extremities%Intravenous injection%Subcutaneous injection%Lower extremity deep venous thrombosis
目的：对比观察经患肢浅静脉注射低分子肝素与皮下注射低分子肝素治疗下肢深静脉血栓形成的疗效。方法413例下肢深静脉血栓形成患者依据确诊日期随机分组,双日纳入实验组(192例),单日纳入对照组(221例)。对照组给予低分子肝素5000 U分2次皮下注射,实验组2500 U经患肢足背浅静脉注射,观察两组患者的疗效。结果实验组治疗1周内、1~2周间和2周以上3个时段治愈病例分别为97例(50.5%)、90例(46.9%)、5例(2.6%)；对照组3个时段治愈病例分别为50例(22.6%)、161例(72.9%)、10例(4.5%)；两组差异有统计学意义(P<0.05)。结论大腿根部扎止血带经患肢足背浅静脉注射药物相当于局部用药,,安全系数大,值得临床推广。
目的：對比觀察經患肢淺靜脈註射低分子肝素與皮下註射低分子肝素治療下肢深靜脈血栓形成的療效。方法413例下肢深靜脈血栓形成患者依據確診日期隨機分組,雙日納入實驗組(192例),單日納入對照組(221例)。對照組給予低分子肝素5000 U分2次皮下註射,實驗組2500 U經患肢足揹淺靜脈註射,觀察兩組患者的療效。結果實驗組治療1週內、1~2週間和2週以上3箇時段治愈病例分彆為97例(50.5%)、90例(46.9%)、5例(2.6%)；對照組3箇時段治愈病例分彆為50例(22.6%)、161例(72.9%)、10例(4.5%)；兩組差異有統計學意義(P<0.05)。結論大腿根部扎止血帶經患肢足揹淺靜脈註射藥物相噹于跼部用藥,,安全繫數大,值得臨床推廣。
목적：대비관찰경환지천정맥주사저분자간소여피하주사저분자간소치료하지심정맥혈전형성적료효。방법413례하지심정맥혈전형성환자의거학진일기수궤분조,쌍일납입실험조(192례),단일납입대조조(221례)。대조조급여저분자간소5000 U분2차피하주사,실험조2500 U경환지족배천정맥주사,관찰량조환자적료효。결과실험조치료1주내、1~2주간화2주이상3개시단치유병례분별위97례(50.5%)、90례(46.9%)、5례(2.6%)；대조조3개시단치유병례분별위50례(22.6%)、161례(72.9%)、10례(4.5%)；량조차이유통계학의의(P<0.05)。결론대퇴근부찰지혈대경환지족배천정맥주사약물상당우국부용약,,안전계수대,치득림상추엄。
Objective To compare and observe curative effect by low molecular weight heparin by intravenous injection and subcutaneous injection in affected limb in the treatment of lower extremity deep venous thrombosis.Methods A total of 413 patients with lower extremity deep venous thrombosis were divided by admission date into experimental group (192 cases) and control group (221 cases). The control group received twice subcutaneous injection of 5000 U low molecular weight heparin, and the experimental group received acrotarsium superficial intravenous injection of 2500 U low molecular weight heparin in affected limb. Curative effects of the two groups were observed.Results The experimental group received treatment for 1 week, during 1~2 weeks, and over 2 weeks, and its healed cases were respectively 97 cases (50.5%), 90 cases (46.9%), 5 cases (2.6%) in the 3 periods, and those in the control group were 50 cases (22.6%), 161 cases (72.9%), and 10 cases (4.5%). The difference had statistical significance between the two groups (P<0.05).Conclusion Implement of tourniquet ligation and acrotarsium superficial intravenous injection in affected limb as local administration provides small possibility of low molecular weight heparin injection bleeding and high safety. This method is worthy of clinical promotion.
