CAJ | 학술논문

目的：观察联合应用痛泻要方和肠胃康治疗肠易激综合征的效果。方法将2013年9月至2014年9月我院收治的87例肝郁脾虚型肠易激综合征患者作为研究对象，将其随机分为治疗组和对照组。为治疗组45例患者联合应用痛泻要方和肠胃康进行治疗，为对照组42例患者采用匹维溴铵进行治疗，然后对比分析其临床疗效及发生不良反应的情况。结果与对照组患者相比，治疗组患者治疗的总有效率较高，差异显著，有统计学意义(P<0.05)。在进行治疗期间，两组患者均未发生严重的不良反应。与对照组患者相比，治疗组患者在进行治疗后其腹痛、腹泻的主症积分较低，差异显著，有统计学意义(P<0.01)。结论联合应用痛泻要方和肠胃康治疗IBS可取得较理想的效果，显著改善患者的临床症状，而且安全性较高，此法值得在临床上推广应用。
목적：관찰연합응용통사요방화장위강치료장역격종합정적효과。방법장2013년9월지2014년9월아원수치적87례간욱비허형장역격종합정환자작위연구대상，장기수궤분위치료조화대조조。위치료조45례환자연합응용통사요방화장위강진행치료，위대조조42례환자채용필유추안진행치료，연후대비분석기림상료효급발생불량반응적정황。결과여대조조환자상비，치료조환자치료적총유효솔교고，차이현저，유통계학의의(P<0.05)。재진행치료기간，량조환자균미발생엄중적불량반응。여대조조환자상비，치료조환자재진행치료후기복통、복사적주증적분교저，차이현저，유통계학의의(P<0.01)。결론연합응용통사요방화장위강치료IBS가취득교이상적효과，현저개선환자적림상증상，이차안전성교고，차법치득재림상상추엄응용。
Objective To observe the clinical effect of Tongxieyaofang(TXYF) combined with Changweikang Granule on irritable bowel syndrome(IBS).Methods Eighty seven cases diagnosed with IBS(Liver depression and spleen deficiency syndrome) were randomly divided into two groups.42 patients in control group were treated with Pinaverium Bromide .Meanwhile,45 patients in the treatment group were treated with TXYF and Changweikang Granule for 4 weeks.The improvement of clinical symptoms and adverse effect were observed. Result The total effective rate was 93.3% and 54.8% in treatment group and control group respectively.There were significant statistical difference between the two groups (P<0.005) .Remission of abdominal pain and diarrhea after treatment in treatment group was significantly better than the control group (P<0.01).No severe adverse effect was observed in both groups. Conclusion TXYF combined with Changweikang Granule have favorable safety and clinical effect on IBS (Liver depression and spleen deficiency syndrome).