中国当代医药
中國噹代醫藥
중국당대의약
China Modern Medicine
2015年
28期
133-135
,共3页
慢性湿疹%接触性皮炎%复方多粘菌素B软膏%复方氟米松软膏
慢性濕疹%接觸性皮炎%複方多粘菌素B軟膏%複方氟米鬆軟膏
만성습진%접촉성피염%복방다점균소B연고%복방불미송연고
Chronic eczema%Contact dermatitis%Compound polymyxin B ointment%Compoun d ointment flumetasone
目的：观察复方多粘菌素B软膏联合复方氟米松软膏治疗慢性湿疹及接触性皮炎的临床效果。方法选择2012年6月~2014年10月于我中心接受治疗的256例慢性湿疹及接触性皮炎患者，将其随机分为研究组(128例)和对照组(128例)。对照组采用单纯复方氟米松软膏治疗，研究组在对照组基础上给予复方多粘菌素B软膏治疗。比较两组患者治疗前后瘙痒程度等临床症状的评分、治疗后14、28 d的临床疗效以及复发率。结果治疗后，两组患者的临床症状均有改善，且研究组的各项评分显著低于对照组(P<0.05)。用药14、28 d后，研究组的治疗总有效率高达66.4%和90.6%，显著高于对照组的39.8%、74.3%(P<0.05)。治疗28 d后，研究组的复发率低于对照组，差异有统计学意义(P<0.05)。结论复方多粘菌素B软膏联合复方氟米松软膏可显著改善慢性湿疹及接触性皮炎患者的临床症状，治疗有效率高，适合临床长期推广应用。
目的：觀察複方多粘菌素B軟膏聯閤複方氟米鬆軟膏治療慢性濕疹及接觸性皮炎的臨床效果。方法選擇2012年6月~2014年10月于我中心接受治療的256例慢性濕疹及接觸性皮炎患者，將其隨機分為研究組(128例)和對照組(128例)。對照組採用單純複方氟米鬆軟膏治療，研究組在對照組基礎上給予複方多粘菌素B軟膏治療。比較兩組患者治療前後瘙癢程度等臨床癥狀的評分、治療後14、28 d的臨床療效以及複髮率。結果治療後，兩組患者的臨床癥狀均有改善，且研究組的各項評分顯著低于對照組(P<0.05)。用藥14、28 d後，研究組的治療總有效率高達66.4%和90.6%，顯著高于對照組的39.8%、74.3%(P<0.05)。治療28 d後，研究組的複髮率低于對照組，差異有統計學意義(P<0.05)。結論複方多粘菌素B軟膏聯閤複方氟米鬆軟膏可顯著改善慢性濕疹及接觸性皮炎患者的臨床癥狀，治療有效率高，適閤臨床長期推廣應用。
목적：관찰복방다점균소B연고연합복방불미송연고치료만성습진급접촉성피염적림상효과。방법선택2012년6월~2014년10월우아중심접수치료적256례만성습진급접촉성피염환자，장기수궤분위연구조(128례)화대조조(128례)。대조조채용단순복방불미송연고치료，연구조재대조조기출상급여복방다점균소B연고치료。비교량조환자치료전후소양정도등림상증상적평분、치료후14、28 d적림상료효이급복발솔。결과치료후，량조환자적림상증상균유개선，차연구조적각항평분현저저우대조조(P<0.05)。용약14、28 d후，연구조적치료총유효솔고체66.4%화90.6%，현저고우대조조적39.8%、74.3%(P<0.05)。치료28 d후，연구조적복발솔저우대조조，차이유통계학의의(P<0.05)。결론복방다점균소B연고연합복방불미송연고가현저개선만성습진급접촉성피염환자적림상증상，치료유효솔고，괄합림상장기추엄응용。
Objective To observe the clinical effect of compound polymyxin B ointment combined with compoun d oint-ment flumetasone in treatment of chronic eczema and contact dermatitis. Methods 256 patients with chronic eczema and contact dermatitis in our centerfrom June 2012 to October 2014 were selected,they were randomly divided into the study group(128 cases) and the control group(128 cases).The control group was treated with simple compound flumeta-sone ointment treatment,the study group was treated with compound ointment flumetasone and compound polymyxin B ointment treatment.The itching degree and other clinical symptoms score before and after treatment,clinical effect of af-ter 14 and 28 d treatment,recurrence rate in two groups were observed. Results After treatment,the clinical symptoms in two groups were improved,the scores in study group were significantly lower than that of control group.After 14 and 28 d treatment,the Total effective rate in study group were respectively 66.4%,90.6%,which were higher than 39.8%and 74.3%of control group.After 28 d treatment,the recurrence rate in study group was lower than that of control group, the differences were statistically significant(P<0.05). Conclusion Compound polymyxin B ointment combined with com-pound ointment flumetasone combination therapy can significantly improve the symptoms of patients with chronic eczema and contact dermatitis,it has high effective rate,and it is suitable for long-term clinical application.
