中国当代医药
中國噹代醫藥
중국당대의약
China Modern Medicine
2015年
28期
27-29
,共3页
无创面罩双水平正压通气%慢性阻塞性肺疾病%呼吸衰竭
無創麵罩雙水平正壓通氣%慢性阻塞性肺疾病%呼吸衰竭
무창면조쌍수평정압통기%만성조새성폐질병%호흡쇠갈
Noninvasive mask bi-level positive airway pressure%Chronic obstructive pulmonary disease%Respiratory failure
目的：探讨无创面罩双水平正压通气(BiPAP)治疗慢性阻塞性肺疾病(COPD)急性加重合并呼吸衰竭的临床效果。方法选取2010年2月~2012年1月我院收治的130例COPD急性加重合并呼吸衰竭患者,按照数字分组法将其分为观察组和对照组,每组65例。两组均给予常规治疗,观察组在常规治疗基础上加用无创面置BiPAP治疗,比较两组患者的临床疗效。结果治疗24h后,两组的PaO2、PaCO2、SaO2和心率均显著性改善(P<0.05),且观察组改善情况优于对照组(P<0.05)。观察组的住院时间为(21.15±4.35)d,短于对照组的(28.21±7.43)d(P<0.05)；观察组的气管插管率为1.54%,显著低于对照组的10.77%(P<0.05)；观察组和对照组的死亡率分别为1.54%、3.08%,两组差异无统计学意义(P跃0.05)。结论无创面置BiPAP治疗COPD急性加重合并呼吸衰竭,可有效改善患者的呼吸功能。即使患者当前状态较稳定,但酌情考虑增加无创通气治疗,可缩短患者的住院时间、改善预后。
目的：探討無創麵罩雙水平正壓通氣(BiPAP)治療慢性阻塞性肺疾病(COPD)急性加重閤併呼吸衰竭的臨床效果。方法選取2010年2月~2012年1月我院收治的130例COPD急性加重閤併呼吸衰竭患者,按照數字分組法將其分為觀察組和對照組,每組65例。兩組均給予常規治療,觀察組在常規治療基礎上加用無創麵置BiPAP治療,比較兩組患者的臨床療效。結果治療24h後,兩組的PaO2、PaCO2、SaO2和心率均顯著性改善(P<0.05),且觀察組改善情況優于對照組(P<0.05)。觀察組的住院時間為(21.15±4.35)d,短于對照組的(28.21±7.43)d(P<0.05)；觀察組的氣管插管率為1.54%,顯著低于對照組的10.77%(P<0.05)；觀察組和對照組的死亡率分彆為1.54%、3.08%,兩組差異無統計學意義(P躍0.05)。結論無創麵置BiPAP治療COPD急性加重閤併呼吸衰竭,可有效改善患者的呼吸功能。即使患者噹前狀態較穩定,但酌情攷慮增加無創通氣治療,可縮短患者的住院時間、改善預後。
목적：탐토무창면조쌍수평정압통기(BiPAP)치료만성조새성폐질병(COPD)급성가중합병호흡쇠갈적림상효과。방법선취2010년2월~2012년1월아원수치적130례COPD급성가중합병호흡쇠갈환자,안조수자분조법장기분위관찰조화대조조,매조65례。량조균급여상규치료,관찰조재상규치료기출상가용무창면치BiPAP치료,비교량조환자적림상료효。결과치료24h후,량조적PaO2、PaCO2、SaO2화심솔균현저성개선(P<0.05),차관찰조개선정황우우대조조(P<0.05)。관찰조적주원시간위(21.15±4.35)d,단우대조조적(28.21±7.43)d(P<0.05)；관찰조적기관삽관솔위1.54%,현저저우대조조적10.77%(P<0.05)；관찰조화대조조적사망솔분별위1.54%、3.08%,량조차이무통계학의의(P약0.05)。결론무창면치BiPAP치료COPD급성가중합병호흡쇠갈,가유효개선환자적호흡공능。즉사환자당전상태교은정,단작정고필증가무창통기치료,가축단환자적주원시간、개선예후。
Objective To explore the clinical effect of noninvasive mask bi-level positive airway pressure (BiPAP) in the treatment of chronic obstructive pulmonary disease(COPD) at acute exacerbation combining with respiratory failure. Methods 130 patients with COPD at acute exacerbation combining with respiratory failure admitted into our hospital from February 2010 to January 2012 were selected.They were divided into the observation group and control group ac-cording to digital grouping method,65 cases in each group.In two groups,conventional treatment were provided.In the observation group,on the basis of the conventional treatment,BiPAP was added.The clinical effect in two groups was compared. Results After 24 h treatment,the levels of PaO2,PaCO2,SaO2 and heart rate in two groups were significantly improved,and the improvement degree in the observation group was better than that of control group(P<0.05).The hospi-tal stay in observation group was (21.15±4.35) d,which was shorter than that of control group(28.21±7.43) d.The intuba-tion rate in observation group was 1.54%, which was significantly less than 10.77% of control group (P<0.05).The mor-tality in observation group and control group were 1.54%,3.08%,the difference was not significant between two groups(P>0.05). Conclusion In the treatment of COPD at acute exacerbation and respiratory failure by noninvasive mask Bi-PAP,can effectively improve patients’ respiratory function.If the current state in patient is stable,where appropriate,Bi-PAP can shorten the length of hospital stay of patients,can improve prognosis.
