中国当代医药
中國噹代醫藥
중국당대의약
China Modern Medicine
2015年
29期
132-134,137
,共4页
咪唑斯汀%荨麻疹%过敏性鼻炎
咪唑斯汀%蕁痳疹%過敏性鼻炎
미서사정%담마진%과민성비염
Mizolastine%Urticarial%Allergic rhinitis
目的：分析咪唑斯汀治疗荨麻疹并发过敏性鼻炎的临床疗效。方法选取2013年3月~2014年8月在我院就诊的75例荨麻疹并发过敏性鼻炎患者，按照治疗方式分为治疗组(40例)和对照组(35例)，治疗组采取咪唑斯汀治疗，对照组采取西替利嗪治疗，对比两组的治疗效果。结果治疗组的临床治疗总有效率为90.0%，显著高于对照组的74.3%(P<0.05)。治疗后，治疗组荨麻疹、过敏性鼻炎症状评分显著低于对照组，荨麻疹、过敏性鼻炎症状改善起效时间显著短于对照组(P<0.05)。两组患者治疗后均未出现肝肾功能异常，仅个别患者出现轻微的头晕、嗜睡、口干，均未影响治疗；两组的不良反应发生率差异无统计学意义(P>0.05)，但治疗组的复发率高于对照组(P<0.05)。结论咪唑斯汀治疗荨麻疹并发过敏性鼻炎的效果显著，具有较高的治疗安全性。
目的：分析咪唑斯汀治療蕁痳疹併髮過敏性鼻炎的臨床療效。方法選取2013年3月~2014年8月在我院就診的75例蕁痳疹併髮過敏性鼻炎患者，按照治療方式分為治療組(40例)和對照組(35例)，治療組採取咪唑斯汀治療，對照組採取西替利嗪治療，對比兩組的治療效果。結果治療組的臨床治療總有效率為90.0%，顯著高于對照組的74.3%(P<0.05)。治療後，治療組蕁痳疹、過敏性鼻炎癥狀評分顯著低于對照組，蕁痳疹、過敏性鼻炎癥狀改善起效時間顯著短于對照組(P<0.05)。兩組患者治療後均未齣現肝腎功能異常，僅箇彆患者齣現輕微的頭暈、嗜睡、口榦，均未影響治療；兩組的不良反應髮生率差異無統計學意義(P>0.05)，但治療組的複髮率高于對照組(P<0.05)。結論咪唑斯汀治療蕁痳疹併髮過敏性鼻炎的效果顯著，具有較高的治療安全性。
목적：분석미서사정치료담마진병발과민성비염적림상료효。방법선취2013년3월~2014년8월재아원취진적75례담마진병발과민성비염환자，안조치료방식분위치료조(40례)화대조조(35례)，치료조채취미서사정치료，대조조채취서체리진치료，대비량조적치료효과。결과치료조적림상치료총유효솔위90.0%，현저고우대조조적74.3%(P<0.05)。치료후，치료조담마진、과민성비염증상평분현저저우대조조，담마진、과민성비염증상개선기효시간현저단우대조조(P<0.05)。량조환자치료후균미출현간신공능이상，부개별환자출현경미적두훈、기수、구간，균미영향치료；량조적불량반응발생솔차이무통계학의의(P>0.05)，단치료조적복발솔고우대조조(P<0.05)。결론미서사정치료담마진병발과민성비염적효과현저，구유교고적치료안전성。
Objective To analysis the clinical effect of mizolastine in treatment of urticaria and allergic rhinitis. Meth-ods 75 patients with urticaria and allergic rhinitis in our hospital from March 2013 to August 2014 were selected.They-were divided into treatment group (n=40) and control group (n=35) according to different therapy measures.The treat-ment group was given mizolastine,the control was given cetirizine.The therapy effect was compared between two groups. Results The total efficient rate in treatment group was 90.0%,which was higher than 74.3%of control group(P<0.05).Af-ter treatment,the symptom scores of urticaria and allergic rhinitis in treatment group were significantly lower than those of control group,urticaria and allergic rhinitis symptoms improved onset time in treatment group were significantly short-er than those of control group(P<0.05).No patient appeared liver and kidney dysfunction before and after treatment.Only individual patients appeared dizziness, drowsiness and dry mouth,the symptoms were mild and did no impact the treat-ment. There was no difference in adverse event between two groups (P>0.05),but the difference of recurrence in two groups was significant (P<0.05). Conclusion Mizolastine has significant effect in treating urticaria and allergic rhinitis, and has higher security.
