中国当代医药
中國噹代醫藥
중국당대의약
China Modern Medicine
2015年
28期
60-62,65
,共4页
朱艳%王翔%董翠婷%武文斌
硃豔%王翔%董翠婷%武文斌
주염%왕상%동취정%무문빈
高通量血液透析%尿毒症患者%失眠程度
高通量血液透析%尿毒癥患者%失眠程度
고통량혈액투석%뇨독증환자%실면정도
High flux hemodialysis%Uremic patients%Sleeplessness degree
目的：探讨高通量血液透析(Hf-HD)对尿毒症患者失眠程度和生活质量的影响。方法选取2012年8月~2014年11月在本院行血液透析的120例尿毒症患者作为研究对象，随机分为Hf-HD组(n=61)和低通量血液透析(Lf-HD)组(n=59)。治疗12周后，通过对其失眠严重程度指数(ISI)、肾脏病生存质量量表(KDQOL-SFTM)相关指标变化的分析，比较两组治疗前后失眠严重程度及生活质量的变化。结果 Hf-HD组治疗后的ISI总分显著低于Lf-HD组，差异有统计学意义(P<0.05)。Hf-HD组的肾病症状、认知功能、睡眠、患者满意度得分显著高于Lf-HD组，差异有统计学意义(P<0.05)。 Hf-HD组的躯体疼痛项得分显著高于Lf-HD组，差异有统计学意义(P<0.01)。 Hf-HD组的生理机能、生理功能、精神健康得分高于Lf-HD组，差异有统计学意义(P<0.05)。结论 Hf-HD通过对较大分子尿毒症毒素的清除，能够有效改善血液透析患者的睡眠质量和相关生活质量。
目的：探討高通量血液透析(Hf-HD)對尿毒癥患者失眠程度和生活質量的影響。方法選取2012年8月~2014年11月在本院行血液透析的120例尿毒癥患者作為研究對象，隨機分為Hf-HD組(n=61)和低通量血液透析(Lf-HD)組(n=59)。治療12週後，通過對其失眠嚴重程度指數(ISI)、腎髒病生存質量量錶(KDQOL-SFTM)相關指標變化的分析，比較兩組治療前後失眠嚴重程度及生活質量的變化。結果 Hf-HD組治療後的ISI總分顯著低于Lf-HD組，差異有統計學意義(P<0.05)。Hf-HD組的腎病癥狀、認知功能、睡眠、患者滿意度得分顯著高于Lf-HD組，差異有統計學意義(P<0.05)。 Hf-HD組的軀體疼痛項得分顯著高于Lf-HD組，差異有統計學意義(P<0.01)。 Hf-HD組的生理機能、生理功能、精神健康得分高于Lf-HD組，差異有統計學意義(P<0.05)。結論 Hf-HD通過對較大分子尿毒癥毒素的清除，能夠有效改善血液透析患者的睡眠質量和相關生活質量。
목적：탐토고통량혈액투석(Hf-HD)대뇨독증환자실면정도화생활질량적영향。방법선취2012년8월~2014년11월재본원행혈액투석적120례뇨독증환자작위연구대상，수궤분위Hf-HD조(n=61)화저통량혈액투석(Lf-HD)조(n=59)。치료12주후，통과대기실면엄중정도지수(ISI)、신장병생존질량량표(KDQOL-SFTM)상관지표변화적분석，비교량조치료전후실면엄중정도급생활질량적변화。결과 Hf-HD조치료후적ISI총분현저저우Lf-HD조，차이유통계학의의(P<0.05)。Hf-HD조적신병증상、인지공능、수면、환자만의도득분현저고우Lf-HD조，차이유통계학의의(P<0.05)。 Hf-HD조적구체동통항득분현저고우Lf-HD조，차이유통계학의의(P<0.01)。 Hf-HD조적생리궤능、생리공능、정신건강득분고우Lf-HD조，차이유통계학의의(P<0.05)。결론 Hf-HD통과대교대분자뇨독증독소적청제，능구유효개선혈액투석환자적수면질량화상관생활질량。
Objective To explore the influence of high flux hemodialysis (Hf-HD) on sleeplessness degree and life quality of uremic patient. Methods 120 uremic patients conducted hemodialysis from August 2012 to November 2014 in our hospital were selected and randomly divided into the Hf-HD group (n=61) and the low flux hemodialysis (Lf-HD) group (n=59).After treatment for 12 weeks,the change of sleeplessness degree and life quality were compared before and after treatment in two groups by analysis of the index change of insomnia severity index (ISI) and kidney disease quali-ty of life sorth form (KDQOL-SFTM). Results The total score of ISI in the Hf-HD group was lower than that in the Lf-HD group,with significant difference(P<0.05).The score of nephropathy symptoms,cognitive function,sleeping and patient sat-isfaction in the Hf-HD group was higher than that in the Lf-HD group,with significant difference (P<0.05).The score of body pain in the Hf-HD group was higher than that in the Lf-HD group,with significant difference(P<0.01).The score of physiological enginery,physiological function and mental health in the Hf-HD group was higher than that in the Lf-HD group,with significant difference(P<0.05). Conclusion Hf-HD by removal large molecule uremic toxin can effective im-prove the sleeping quality and related life quality of hemodialysis patients.
