CAJ | 학술논문

目的：探讨步长脑心通治疗冠心病不稳定型心绞痛的效果。方法选取本院2012年9月~2014年12月收治的360例冠心病不稳定型心绞痛患者作为研究对象，随机分为观察组和对照组，各180例。观察组在常规西医治疗的基础上加用步长脑心通，对照组在常规西医治疗的基础上加用复方丹参片。比较两组治疗前后的心绞痛发作情况及缺血性心电图S-T段下降程度，记录两组的不良反应发生率及血液流变学等指标变化。结果观察组治疗后的心绞痛发作频率显著少于对照组，持续时间显著短于对照组，缺血性心电图S-T段下降程度显著低于对照组，差异有统计学意义(P<0.05)。观察组治疗后的血液流变学指标水平显著低于对照组，差异有统计学意义(P<0.05)。观察组的不良反应发生率显著低于对照组，差异有统计学意义(P<0.05)。结论步长脑心通治疗冠心病不稳定型心绞痛效果显著，可明显降低心绞痛发作频率及缺血性心电图S-T段下降程度，有效改善血液流变学指标，具有不良反应少、可控性较强、起效快等优势，值得临床推广应用。
목적：탐토보장뇌심통치료관심병불은정형심교통적효과。방법선취본원2012년9월~2014년12월수치적360례관심병불은정형심교통환자작위연구대상，수궤분위관찰조화대조조，각180례。관찰조재상규서의치료적기출상가용보장뇌심통，대조조재상규서의치료적기출상가용복방단삼편。비교량조치료전후적심교통발작정황급결혈성심전도S-T단하강정도，기록량조적불량반응발생솔급혈액류변학등지표변화。결과관찰조치료후적심교통발작빈솔현저소우대조조，지속시간현저단우대조조，결혈성심전도S-T단하강정도현저저우대조조，차이유통계학의의(P<0.05)。관찰조치료후적혈액류변학지표수평현저저우대조조，차이유통계학의의(P<0.05)。관찰조적불량반응발생솔현저저우대조조，차이유통계학의의(P<0.05)。결론보장뇌심통치료관심병불은정형심교통효과현저，가명현강저심교통발작빈솔급결혈성심전도S-T단하강정도，유효개선혈액류변학지표，구유불량반응소、가공성교강、기효쾌등우세，치득림상추엄응용。
Objective To explore the effect of Buchang Naoxintong in the treatment of unstable angina pectoris of coro-nary heart disease (CHD). Methods 360 CHD patients with unstable angina pectoris from September 2012 to December 2014 in our hospital were selected and randomly divided into the observation group and the control group,180 cases in each group.The observation group was given Buchang Naoxintong group on the basis of the conventional western medicine,the control group was given compound Danshen tablet on the basis of conventional western medicine.The oc-currence of angina pectoris,decreasing degree of ischemic S-T segment in electrocardiograph before and after treatment weas compared in two groups. The incidence rate of adverse reaction and hemorheology was recorded. Results The fre-quency of angina pectoris attack in the observation group was less than that in the control group,the duration time in the observation group was shorter than that in the control group,the degree of S-T segment depression in the observa-tion group was lower than that in the control group,with significant difference (P<0.05).The level of blood flow change in the observation group were lower than that in the control group,with significant difference (P<0.05).The incidence of adverse reaction in observation group was lower than that in control group,with significant difference (P<0.05). Con-clusion The effect of Buchang Naoxintong in the treatment of unstable angina pectoris of coronary heart disease is sig-nificant,which can greatly reduce occurrence of angina pectoris and decreasing degree of ischemic S-T segment in ECG,effectively improve hemorheological indexes,has the advantages of less adverse reaction,better controllability and quicker effect,it is worthy of popularize and application.