CAJ | 학술논문

目的利用ECLIPSE计划系统对局部晚期喉癌适形放疗(3DCRT)和逆向调强适形放疗( IMRT)计划作剂量学比较,评估不同照射方法的优缺点. 方法选择6例病理证实的局部晚期喉癌患者,用ECLIPSE对每例患者分别作出3DCRT和IMRT计划. 根据靶区V95%、D5%、D95%、靶区最大值、最小值及平均值和正常组织受量D50、D33、D5、Dmax和Dmean来比较这两种计划剂量学的差异. 结果两种不同计划中的靶区分布中,GTV和GTVnd差别不大,但对于亚临床区CTV和某些正常组织有统计学差异. 结论对局部晚期喉癌原发灶及阳性淋巴结,3DCRT和IMRT计划均有较好覆盖. 但在亚临床病灶方面,IMRT比3DCRT包含靶区更好一些,且IMRT减少了腮腺正常组织的照射剂量.
목적 이용ECLIPSE계화계통대국부만기후암괄형방료(3DCRT)화역향조강괄형방료( IMRT)계화작제량학비교,평고불동조사방법적우결점. 방법 선택6례병리증실적국부만기후암환자,용ECLIPSE대매례환자분별작출3DCRT화IMRT계화. 근거파구V95%、D5%、D95%、파구최대치、최소치급평균치화정상조직수량D50、D33、D5、Dmax화Dmean래비교저량충계화제량학적차이. 결과 량충불동계화중적파구분포중,GTV화GTVnd차별불대,단대우아림상구CTV화모사정상조직유통계학차이. 결론 대국부만기후암원발조급양성림파결,3DCRT화IMRT계화균유교호복개. 단재아림상병조방면,IMRT비3DCRT포함파구경호일사,차IMRT감소료시선정상조직적조사제량.
Obejctive To compare the differences between conventional radiation therapy (3DCRT) and intensity modulated radiation therapy( IMRT) for locally advanced laryngeal carcinoma patients by ECLIPSE treat -ment planning system.Methods Six locally advanced laryngeal carcinoma patients ′treatment plans were de-signed as IMRT and 3DCRT according to ECLIPSE treatment planning system ,respectively.The following values were measured,such as V95%、D5%、D95%、Dmin and D mean of the target volume,and the D50,D33,D5, Dmax and Dmean of normal tissues.Results The dose coverage rate of GTV and GTVnd in the IMRT plan was compared to ECLIPSE treatment planning system with no statistical differences.However, there were obvious difference in CTV and some normal tissues.Conclusion Both IMRT and 3DCRT have good coverage to primary tumor and metastatic lymph nodes.IMRT can spare the parotid from high dose irradiation.