医学综述
醫學綜述
의학종술
Medical Recapitulate
2015年
19期
3464-3466
,共3页
辛荣荣%于艳红%孙文君%孙飞(综述)%高冬梅(审校)
辛榮榮%于豔紅%孫文君%孫飛(綜述)%高鼕梅(審校)
신영영%우염홍%손문군%손비(종술)%고동매(심교)
经前烦躁症%负性情绪%脑区%神经回路
經前煩躁癥%負性情緒%腦區%神經迴路
경전번조증%부성정서%뇌구%신경회로
Premenstrual dysphoric disorder%Negative emotion%Brain areas%Neural circuits
经前烦躁症( PMDD)的临床表现复杂多样,是育龄期妇女的常见病、多发病,直接影响女性生活质量。其发病机制十分复杂,近年来,国内外学者从神经机制及脑区活性变化来揭示PMDD的发病原因。相关研究显示,前额叶、杏仁核、海马及小脑、岛叶等脑区的活性变化可能与PMDD发病密切相关,现对涉及该病的脑区及脑区间的相互联系进行综述,为明确经前期综合征的神经机制研究提供参考依据。
經前煩躁癥( PMDD)的臨床錶現複雜多樣,是育齡期婦女的常見病、多髮病,直接影響女性生活質量。其髮病機製十分複雜,近年來,國內外學者從神經機製及腦區活性變化來揭示PMDD的髮病原因。相關研究顯示,前額葉、杏仁覈、海馬及小腦、島葉等腦區的活性變化可能與PMDD髮病密切相關,現對涉及該病的腦區及腦區間的相互聯繫進行綜述,為明確經前期綜閤徵的神經機製研究提供參攷依據。
경전번조증( PMDD)적림상표현복잡다양,시육령기부녀적상견병、다발병,직접영향녀성생활질량。기발병궤제십분복잡,근년래,국내외학자종신경궤제급뇌구활성변화래게시PMDD적발병원인。상관연구현시,전액협、행인핵、해마급소뇌、도협등뇌구적활성변화가능여PMDD발병밀절상관,현대섭급해병적뇌구급뇌구간적상호련계진행종술,위명학경전기종합정적신경궤제연구제공삼고의거。
Premenstrual dysphoric disorder(PMDD) has complex and diverse clinical manifestations. PMDD is a common disease to women of childbearing age and has a direct impact on women′s life quality. Its pathogenesis is complex,in recent years,scholars have been trying to reveal the etiology of PMDD from the neu-ral mechanisms and brain activity. But so far,neuroimaging studies about emotional processing is not yet con-clusive. The disease may be closely associated with brain regions including the prefrontal cortex,amygdala,hip-pocampus and cerebellum,insula. Here is to make a review of the development of brain areas involved in the disease and the interactions,with expectation to provide references on neural mechanisms for PMDD.