中国中医眼科杂志
中國中醫眼科雜誌
중국중의안과잡지
Chinese Journal of Chinese Ophthalmology
2015年
4期
265-268
,共4页
柔肝健脾法%针灸%年龄相关性黄斑变性%疗效分析
柔肝健脾法%針灸%年齡相關性黃斑變性%療效分析
유간건비법%침구%년령상관성황반변성%료효분석
emolliating the liver and fortifying the spleen method%acupuncture%age-related macular degen-eration%outcome analysis
目的：观察柔肝健脾法合并针刺治疗年龄相关性黄斑变性（ARMD）的临床疗效。方法2012年8月至2014年1月收集门诊符合纳入标准的干性ARMD（肝肾阴虚型）和湿性黄斑变性（脾虚湿困型）共80例，随机分为中药合并针刺治疗组（治疗组）和中成药加维生素E对照组（对照组）。治疗组在针刺治疗的同时，对干性ARMD者，予柔肝健脾、补益肝肾中药，对湿性ARMD者，予柔肝健脾、温阳利水中药。对照组干性、湿性患者均予口服复方血塞通胶囊和维生素E胶囊。2组的总疗程均为3个月，比较2组患者在治疗1个月及3个月时的视力和中医证侯积分的变化差异。结果治疗组共42例（47只眼），对照组共38例（40只眼）。2组患者性别、年龄、ARMD分型差异无统计学意义（P＞0.05）。视力疗效：治疗后1个月，治疗组显效16只眼，有效23只眼，无效8只眼，总有效率82.98%，对照组显效3只眼，有效11只眼，无效26只眼，总有效率35.00%（有效率比较c2=20.89，P=0.001）；治疗后3个月，治疗组显效17只眼，有效25只眼，无效5只眼，总有效率89.36%，对照组显效6只眼，有效13只眼，无效21只眼，总有效率47.50%（有效率比较c2=18.07， P=0.001）。中医证候疗效：治疗后1个月，治疗组显效12例，有效24例，无效6例，对照组显效6例，有效10例，无效22例（Z=-3.472，P=0.001）；治疗后3个月，治疗组显效16例，有效22例，无效4例，对照组显效8例，有效11例，无效19例（Z=-3.319，P=0.001）。即治疗组在治疗1个月、3个月时的视力及中医证候改善情况均好于对照组。结论柔肝健脾法配合针刺治疗可以明显改善ARMD患者的视力及中医症状，对ARMD有一定的治疗效果。
目的：觀察柔肝健脾法閤併針刺治療年齡相關性黃斑變性（ARMD）的臨床療效。方法2012年8月至2014年1月收集門診符閤納入標準的榦性ARMD（肝腎陰虛型）和濕性黃斑變性（脾虛濕睏型）共80例，隨機分為中藥閤併針刺治療組（治療組）和中成藥加維生素E對照組（對照組）。治療組在針刺治療的同時，對榦性ARMD者，予柔肝健脾、補益肝腎中藥，對濕性ARMD者，予柔肝健脾、溫暘利水中藥。對照組榦性、濕性患者均予口服複方血塞通膠囊和維生素E膠囊。2組的總療程均為3箇月，比較2組患者在治療1箇月及3箇月時的視力和中醫證侯積分的變化差異。結果治療組共42例（47隻眼），對照組共38例（40隻眼）。2組患者性彆、年齡、ARMD分型差異無統計學意義（P＞0.05）。視力療效：治療後1箇月，治療組顯效16隻眼，有效23隻眼，無效8隻眼，總有效率82.98%，對照組顯效3隻眼，有效11隻眼，無效26隻眼，總有效率35.00%（有效率比較c2=20.89，P=0.001）；治療後3箇月，治療組顯效17隻眼，有效25隻眼，無效5隻眼，總有效率89.36%，對照組顯效6隻眼，有效13隻眼，無效21隻眼，總有效率47.50%（有效率比較c2=18.07， P=0.001）。中醫證候療效：治療後1箇月，治療組顯效12例，有效24例，無效6例，對照組顯效6例，有效10例，無效22例（Z=-3.472，P=0.001）；治療後3箇月，治療組顯效16例，有效22例，無效4例，對照組顯效8例，有效11例，無效19例（Z=-3.319，P=0.001）。即治療組在治療1箇月、3箇月時的視力及中醫證候改善情況均好于對照組。結論柔肝健脾法配閤針刺治療可以明顯改善ARMD患者的視力及中醫癥狀，對ARMD有一定的治療效果。
목적：관찰유간건비법합병침자치료년령상관성황반변성（ARMD）적림상료효。방법2012년8월지2014년1월수집문진부합납입표준적간성ARMD（간신음허형）화습성황반변성（비허습곤형）공80례，수궤분위중약합병침자치료조（치료조）화중성약가유생소E대조조（대조조）。치료조재침자치료적동시，대간성ARMD자，여유간건비、보익간신중약，대습성ARMD자，여유간건비、온양이수중약。대조조간성、습성환자균여구복복방혈새통효낭화유생소E효낭。2조적총료정균위3개월，비교2조환자재치료1개월급3개월시적시력화중의증후적분적변화차이。결과치료조공42례（47지안），대조조공38례（40지안）。2조환자성별、년령、ARMD분형차이무통계학의의（P＞0.05）。시력료효：치료후1개월，치료조현효16지안，유효23지안，무효8지안，총유효솔82.98%，대조조현효3지안，유효11지안，무효26지안，총유효솔35.00%（유효솔비교c2=20.89，P=0.001）；치료후3개월，치료조현효17지안，유효25지안，무효5지안，총유효솔89.36%，대조조현효6지안，유효13지안，무효21지안，총유효솔47.50%（유효솔비교c2=18.07， P=0.001）。중의증후료효：치료후1개월，치료조현효12례，유효24례，무효6례，대조조현효6례，유효10례，무효22례（Z=-3.472，P=0.001）；치료후3개월，치료조현효16례，유효22례，무효4례，대조조현효8례，유효11례，무효19례（Z=-3.319，P=0.001）。즉치료조재치료1개월、3개월시적시력급중의증후개선정황균호우대조조。결론유간건비법배합침자치료가이명현개선ARMD환자적시력급중의증상，대ARMD유일정적치료효과。
OBJECTIVE To observe the clinical efficacy of combined acupuncture and emolliating the liver and fortifying the spleen method for the treatment of age-related macular degeneration. METHODS From August 2012 to January 2014, 80 cases which have fulfilled the clinical inclusion criteria of age-related macular degenera-tion (liver kidney yin deficiency type) and wet macular degeneration (splenasthenic Hygrosis type ) were collected and randomly divided into traditional Chinese medicine decoction combined with acupuncture therapy group and patterned traditional Chinese medication plus vitamin E group. Patients in the treatment group were given both oral decoction with efficacy of emolliating the liver and fortifying the spleen and orbit acupuncture treatment, patients in the control group were treated with oral compound Xuesaitong capsules and vitamin E capsules, total intervention course 3 months.Visual acuity, visual field, TCM clinical findings were evaluated before and after the intervention in both groups. RESULTS There were 42 enrolled cases in the decoction combined with acupuncture treatment group;There were 38 cases in the control group. No significant difference on general information such as gender, age distri-bution, ARMD types between the two groups were found(P<0.05). visual effect:After 1 month of treatment group vi-sion:excellent 16 eyes ,valid 23 eyes, invalid 8 eyes. Total effective rate 82.98%;the control group vision:excellent 3 eyes, valid 11 eyes, invalid 26 eyes. Total effective rate 35.00%, (comparison of the total efficiency c2=20.89,P=0.001);After 3 month of treatment group vision:excellent 17 eyes ,valid 25 eyes, invalid 5 eyes. Total effective rate 89.36%;the control group vision:excellent 6 eyes ,valid 13 eyes, invalid 21 eyes. Total effective rate 47.50%, (com-parison of the total efficiency c2=18.07,P=0.001). The effective of syndrome:After1 month of treatment group:ex-cellent 12 cases, valid 24 cases, invalid 6 cases, the control group:excellent 6 cases, valid 10 cases, invalid 22 cases (Z=-3.472,P=0.001);After 3 month of treatment group:excellent 16 cases ,valid 22 cases, invalid 4 cases, the con-trol group:excellent 8 cases ,valid 11 cases, invalid 19 cases(Z=-3.319,P=0.001). Treatment group in the treatment of 1 and 3 months of vision and improvement of syndromes are better than the control group. CONCLUSIONS E-molliating the liver and fortifying the spleen method combined acupuncture therapy could significantly improve vi-sion and TCM symptoms of patients with macular degeneration, and this approach for the macular degeneration had certain effect .
