CAJ | 학술논문

目的：研究饮酒对宜昌市职业人群代谢综合征（MS）患病率及其相关因素的影响，为该市MS人群生活方式干预提供决策依据。方法抽样调查宜昌市15个单位职业人群共3640人（男2285人，女1355人，年龄20～70岁），详细询问其饮酒习惯并填写调查表，进行体格检查和实验室检查，根据日饮酒量分为3组（不饮和偶尔饮酒组、适量饮酒组、过量饮酒组），对结果进行统计分析。结果与不饮和偶尔饮酒组比较，适量饮酒组MS患病率及体质量指数（BMI）、舒张压（DBP）、三酰甘油（TG）、尿酸（UA）异常率显著升高（P＜0．05），收缩压（SBP）异常率显著下降（P＜0．05）；过量饮酒组BMI、DBP、SBP、葡萄糖（GLU）、总胆固醇（TCH）、TG、低密度脂蛋白胆固醇（LDL‐C）、UA、MS患病率显著升高（P＜0．05）。与适量饮酒组比较，过量饮酒组MS患病率及BMI、DBP、GLU、TCH、TG、LDL‐C、UA异常率上升显著（P＜0．05）。不论适量还是过量饮酒，C‐反应蛋白（CRP）及高密度脂蛋白胆固醇（HDL‐C）异常率没有显著变化（P＞0．05）。结论适量饮酒对宜昌市职业人群BMI、DBP、TG、LDL‐C、UA有显著影响，对GLU、TCH、HDL‐C、CRP影响不明显。MS患病率及其相关因素异常率与乙醇摄入量呈正相关。适量饮酒有降低SBP和GLU作用，但不能降低MS发病率。
목적：연구음주대의창시직업인군대사종합정（MS）환병솔급기상관인소적영향，위해시MS인군생활방식간예제공결책의거。방법추양조사의창시15개단위직업인군공3640인（남2285인，녀1355인，년령20～70세），상세순문기음주습관병전사조사표，진행체격검사화실험실검사，근거일음주량분위3조（불음화우이음주조、괄량음주조、과량음주조），대결과진행통계분석。결과여불음화우이음주조비교，괄량음주조MS환병솔급체질량지수（BMI）、서장압（DBP）、삼선감유（TG）、뇨산（UA）이상솔현저승고（P＜0．05），수축압（SBP）이상솔현저하강（P＜0．05）；과량음주조BMI、DBP、SBP、포도당（GLU）、총담고순（TCH）、TG、저밀도지단백담고순（LDL‐C）、UA、MS환병솔현저승고（P＜0．05）。여괄량음주조비교，과량음주조MS환병솔급BMI、DBP、GLU、TCH、TG、LDL‐C、UA이상솔상승현저（P＜0．05）。불론괄량환시과량음주，C‐반응단백（CRP）급고밀도지단백담고순（HDL‐C）이상솔몰유현저변화（P＞0．05）。결론괄량음주대의창시직업인군BMI、DBP、TG、LDL‐C、UA유현저영향，대GLU、TCH、HDL‐C、CRP영향불명현。MS환병솔급기상관인소이상솔여을순섭입량정정상관。괄량음주유강저SBP화GLU작용，단불능강저MS발병솔。
Objective To study the relationships of alcohol consumption to the prevalence of metabolic syndrome and its re‐lated components in Yichang professional population and provide decision making basis for lifestyle intervention to MS crowd in the city .Methods We examined baseline data from 3 640 participants (2 285 men and 1 355 women) aged 20 to 70 years who under‐went a careful drinking habits survey ,then physical examination and blood chemical examination .They were divided into three groups by average ethanol intake [non ,occasional (<10 g/day) ,moderate (≥10 and <30 g/day) ,and heavy (≥30 g/day) drink‐ers] .Results Compared with no drinking and occasional drinking group ,the prevalence of MS and abnormal rate of BMI ,DBP ,TG , UA increased significantly (P< 0 .05) while SBP decreased significantly in moderate drinking group;compared with moderate drinking group ,the prevalence of MS and abnormal rate of BMI ,DBP and SBP ,GLU ,TCH ,TG ,LDL C ,UA increased significantly (P<0 .05) in heavy alcohol consumption group;whether moderate or heavy drinking ,abnormal rate of CRP and HDL C did not change significantly(P>0 .05) .Conclusion Even moderate drinking has a significant effect to BMI ,DBP ,TG ,LDL C ,UA ,but not obvious to CRP ,GLU ,TCH ,HDL C .Excessive alcohol consumption has a very bad effect on BMI ,DBP ,SBP ,GLU ,TCH ,TG , HDL C ,LDL C ,UA .Both the prevalence of MS and the abnormal rate of its related components are proportional to the alcohol in‐take .Although moderate drinking could lower SBP and GLU ,but can not reduce the incidence of MS .