CAJ | 학술논문

目的：综合评价针刺联合中药疗法对治疗前部缺血性视神经病变的有效性。方法计算机检索Medline/PubMed、中国生物医学文摘（CBM）、中国知网（CNKI）、中文期刊全文（VIP）及万方数字化期刊全文等数据库中建库至2014年11月以前，公开发表的针刺配合中药联合治疗前部缺血性视神经病变的随机对试验。应用RevMan 5.2.7软件进行循证医学评价。结果符合纳入标准的文献9篇，共796只眼，针刺联合中药疗法优于单纯常规药物治疗，差异有统计学意义：总有效率比值比（OR）=3.50，95%可信区间（CI）2.41~5.09；视野缺损范围均数差（MD）=-8.33，95%CI-11.48~-5.17；平均光敏感度MD=2.07，95%CI 1.02~3.13。结论针刺联合中药治疗前部缺血性视神经病变疗效优于单纯常规药物治疗，但因本次纳入文献数量和质量存在一定局限，未来仍需多中心大样本的临床试验，以提高针药联合疗效的证据强度。
목적：종합평개침자연합중약요법대치료전부결혈성시신경병변적유효성。방법계산궤검색Medline/PubMed、중국생물의학문적（CBM）、중국지망（CNKI）、중문기간전문（VIP）급만방수자화기간전문등수거고중건고지2014년11월이전，공개발표적침자배합중약연합치료전부결혈성시신경병변적수궤대시험。응용RevMan 5.2.7연건진행순증의학평개。결과부합납입표준적문헌9편，공796지안，침자연합중약요법우우단순상규약물치료，차이유통계학의의：총유효솔비치비（OR）=3.50，95%가신구간（CI）2.41~5.09；시야결손범위균수차（MD）=-8.33，95%CI-11.48~-5.17；평균광민감도MD=2.07，95%CI 1.02~3.13。결론침자연합중약치료전부결혈성시신경병변료효우우단순상규약물치료，단인본차납입문헌수량화질량존재일정국한，미래잉수다중심대양본적림상시험，이제고침약연합료효적증거강도。
OBJECTIVE To evaluate the efficacy of acupuncture combined with Chinese medicine treatment for anterior ischemic optic neuropathy (AION). METHODS Medline, Web of Science, Chinese Biomedical Litera-ture (CBM), China Academic Journal Network Publishing (CNKI), China info and VIP were retrievaled on the RCTs of acupuncture combined with Chinese medicine treatment for anterior ischemic optic neuropathy, time limitation from database established to November, 2014, RevMan 5.2.7 was used to analysis the data. RESULTS Nine re-searches and 796 eyes were selected for the study. Analysis data showed an overall OR comparing the acupuncture combined with Chinese medicine to control condition was 3.50, 95%CI:2.41~5.09;Visual field defects:MD=-8.33, 95%CI:-11.48~-5.17;Visual acuity:MD=2.07,95%CI:1.02~3.13. CONCLUSIONS Associated acupuncture and traditional Chinese medicine therapy was effective for AION. Due to limitations of the quantity and quality of includ-ed studies, this conclusion has yet to be carried out in large, multicenter study to verify.