化工技术与开发
化工技術與開髮
화공기술여개발
Technology & Development of Chemical Industry
2015年
10期
10-12
,共3页
红树林%内生真菌%代谢产物
紅樹林%內生真菌%代謝產物
홍수림%내생진균%대사산물
mangrove%endophytic fungus%metabolites
研究南海红树林内生真菌Sk-3的代谢产物，采用反复硅胶柱色谱法、Sephadex LH-20凝胶色谱法等进行分离纯化，并通过理化常数测定和光谱分析鉴定其化学结构。从南海红树林内生真菌Sk-3的菌体中分离得到4个代谢产物。经波谱解析，分别为3-(羟甲基)-6,8-二甲氧基香豆素(1)，4-(Hydroxymethyl)-7-methoxy-6-methyl-1(3H)-isobenzofuranone(2)，环（苯丙-苯丙）二肽(3)，环(苯丙-酪)肽(4)。所有化合物均首次从南海红树林内生真菌Sk-3中分离得到。
研究南海紅樹林內生真菌Sk-3的代謝產物，採用反複硅膠柱色譜法、Sephadex LH-20凝膠色譜法等進行分離純化，併通過理化常數測定和光譜分析鑒定其化學結構。從南海紅樹林內生真菌Sk-3的菌體中分離得到4箇代謝產物。經波譜解析，分彆為3-(羥甲基)-6,8-二甲氧基香豆素(1)，4-(Hydroxymethyl)-7-methoxy-6-methyl-1(3H)-isobenzofuranone(2)，環（苯丙-苯丙）二肽(3)，環(苯丙-酪)肽(4)。所有化閤物均首次從南海紅樹林內生真菌Sk-3中分離得到。
연구남해홍수림내생진균Sk-3적대사산물，채용반복규효주색보법、Sephadex LH-20응효색보법등진행분리순화，병통과이화상수측정화광보분석감정기화학결구。종남해홍수림내생진균Sk-3적균체중분리득도4개대사산물。경파보해석，분별위3-(간갑기)-6,8-이갑양기향두소(1)，4-(Hydroxymethyl)-7-methoxy-6-methyl-1(3H)-isobenzofuranone(2)，배（분병-분병）이태(3)，배(분병-락)태(4)。소유화합물균수차종남해홍수림내생진균Sk-3중분리득도。
Secondary metabolites of mangrove endophytic fungus No. Sk-3 from the south China sea was studied. The compounds were isolated by column chromatography and identified on the basia of physic-chemical constants and spectral analysis. Four me-tabolites were obtained and elucidated:3-(hydroxymethyl)-6,8-dimthoxy-2H-chromen-2-one (1), 4-(Hydroxymethyl)-7-methoxy-6-methyl-1(3H)-isobenzofuranone(2), [cyclo-(Phe-phe) (3), cy lo ( Phe-Tyr) (4). The four metabolites were obtained from endophytic fungus No. Sk-3 for the first time.
