CAJ | 학술논문

脑卒中是一种以脑血液循环障碍为主要表现的疾病,在脑卒中的发病过程中,脑细胞凋亡相关因子的动态表达与调控是目前神经病学领域研究的重要方向.笔者查阅相关文献,综述了Caspases蛋白家族、Bcl-2蛋白家族、细胞色素C (cytochrome complex,cyt-c)、即早反应基因c-fos、p53基因、Fas基因对脑卒中的重要作用及影响机制.
뇌졸중시일충이뇌혈액순배장애위주요표현적질병,재뇌졸중적발병과정중,뇌세포조망상관인자적동태표체여조공시목전신경병학영역연구적중요방향.필자사열상관문헌,종술료Caspases단백가족、Bcl-2단백가족、세포색소C (cytochrome complex,cyt-c)、즉조반응기인c-fos、p53기인、Fas기인대뇌졸중적중요작용급영향궤제.
Stroke is characterized by the sudden loss of cerebral blood circulation. In the pathology course of stroke, dynamic expression and regulation of apoptosis related factors in brain have become an important direction of current research in the field of neurology. The author reviewes related literatures and summerizes important effects and underlying mechanism of apoptosis family on stroke, such as Caspases protein family, Bcl-2 protein family, cytochrome complex(cyt-c), early response genec-fos,p53 gene andFas gene.