CAJ | 학술논문

糖尿病视网膜病变动物模型的制备方法有多种，其中化学诱导的动物模型因其来源简单、方法简便、经济、并发症少等优点而被广泛应用。本文就现在常用的化学诱导的糖尿病视网膜病变动物模型的构建、药物类别、使用剂量、给药途径、成模标准、动物种属、成模时间等方面进行阐述，同时简要说明体内成像技术在这些模型中的特征性表现，为研究人员了解以及选择合适的动物模型进行研究提供参考。
당뇨병시망막병변동물모형적제비방법유다충，기중화학유도적동물모형인기래원간단、방법간편、경제、병발증소등우점이피엄범응용。본문취현재상용적화학유도적당뇨병시망막병변동물모형적구건、약물유별、사용제량、급약도경、성모표준、동물충속、성모시간등방면진행천술，동시간요설명체내성상기술재저사모형중적특정성표현，위연구인원료해이급선택합괄적동물모형진행연구제공삼고。
There are many different kinds of preparation methods to make animal models of diabetic retinopathy. Chemical induced animal models are widely used because of its simple source and method, cheap and less complications. This article showed the method, drug category, dosage, drug-delivery way, standards, animal species and time for success, etc, and briefly introduced the expression by body characteristic imaging technology in these models. It provided the reference for researchers to understand and choose the suitable animal model for research.