CAJ | 학술논문

目的：探讨纤维蛋白单体（FM ）、D‐二聚体（D‐D）等凝血指标检测在诊断产科早期DIC诊断中的意义。方法对90例健康的体检妇女（对照组）、270例正常妊娠的妇女（早、中、晚孕各90例）、36例产科早期DIC患者（早期DIC组）进行纤维蛋白单体（FM）、D‐二聚体（D‐D）、凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、纤维蛋白原（FIB）水平的检测。结果早期DIC组FM、D‐D水平高于对照组和妊娠组各期（P＜0．05）；晚孕组PT、APTT比早、中孕组及对照组明显缩短，FIB明显升高，差异均有统计学意义（P＜0．05）。结论 PT、APTT、FIB能反映妊娠晚期血液处于高凝状态，但不能诊断产科早期DIC ，对于产科早期DIC的诊断，FM、D‐D具有重要价值。
목적：탐토섬유단백단체（FM ）、D‐이취체（D‐D）등응혈지표검측재진단산과조기DIC진단중적의의。방법대90례건강적체검부녀（대조조）、270례정상임신적부녀（조、중、만잉각90례）、36례산과조기DIC환자（조기DIC조）진행섬유단백단체（FM）、D‐이취체（D‐D）、응혈매원시간（PT）、활화부분응혈활매시간（APTT）、섬유단백원（FIB）수평적검측。결과조기DIC조FM、D‐D수평고우대조조화임신조각기（P＜0．05）；만잉조PT、APTT비조、중잉조급대조조명현축단，FIB명현승고，차이균유통계학의의（P＜0．05）。결론 PT、APTT、FIB능반영임신만기혈액처우고응상태，단불능진단산과조기DIC ，대우산과조기DIC적진단，FM、D‐D구유중요개치。
Objective To investigate the significance of fibrin monomer(FM ) ,D‐Dimer(D‐D) and other blood coagulation indica‐tors detection in the early diagnosis of disseminated intravascular coagulation(DIC) in obstetrics .Methods 90 healthy women with‐out pregnancy(control group) ,270 normal pregnant women including early ,mid‐,late pregnancy(90 cases for each) ,36 early DIC puerperas(early DIC group) were enrolled in the study .FM ,D‐D ,prothrombin time (PT ) ,activated partial coagulation activity (APTT) ,fibrinogen(FIB) levels were detected for those people .Results The levels of D‐D and FM in early DIC group were signif‐icantly higher than those in control group (P<0 .05) ,and PT ,APTT in late pregnant group were significantly shorter than those in early ,mid‐pregnant group and control group ,while FIB was significantly higher ,the difference was statistically significant(P<0 .05) .Conclusion PT ,APTT and FIB can reflect the high blood coagulation state in the late pregnancy ,but can not be used in the diagnosis of early DIC .D‐D and FM have important value for the early diagnosis of DIC in obstetrics .