CAJ | 학술논문

目的：了解中山地区人群中红细胞葡萄糖‐6‐磷酸脱氢酶（G6PD）缺乏症的发病情况。方法选取2012～2013年中山地区进行G6PD活性检测的新生儿、育龄人群和有相应临床症状的疑似患者。采用紫外速率法检测上述人群红细胞中G6PD活性。结果在受检者中共检出G6 PD缺乏1030例，检出率为4．37％（1030／23595）；男性中的检出率为9．42％（513／5447）；女性中的检出率为2．85％（517／18148）。结论中山地区是G6PD缺乏症的高发地区，应注意在育龄人群和新生儿中进行该疾病的筛查，以降低G6 PD缺乏症的发病率及预防其引起的并发症。
목적：료해중산지구인군중홍세포포도당‐6‐린산탈경매（G6PD）결핍증적발병정황。방법선취2012～2013년중산지구진행G6PD활성검측적신생인、육령인군화유상응림상증상적의사환자。채용자외속솔법검측상술인군홍세포중G6PD활성。결과재수검자중공검출G6 PD결핍1030례，검출솔위4．37％（1030／23595）；남성중적검출솔위9．42％（513／5447）；녀성중적검출솔위2．85％（517／18148）。결론중산지구시G6PD결핍증적고발지구，응주의재육령인군화신생인중진행해질병적사사，이강저G6 PD결핍증적발병솔급예방기인기적병발증。
Objective To estimate the prevalence of Glucose‐6‐phosphate dehydrogenase(G6PD) deficiency in Zhongshan area . Methods The activity of G6PD in red blood cells was determined by using ultra‐violet rate method for neonates ,couples of child‐bearing age and suspected patients who had clinical symptoms in Zhongshan area from 2012 to 2013 .Results The total detection rate of G6PD deficiency was 4 .37% (1 030/23 595);in male the detection rate was 9 .42% (513/5 447);in female the detection rate was 2 .85% (517/18 148) .Conclusion The incidence of G6PD deficiency were high in Zhongshan area .Therefore ,more attention should be paid to the screening of the disease in neonates and couples of childbearing age so as to reduce the incidence of G6PD defi‐ciency and prevent the complications caused by the disease .