特产研究
特產研究
특산연구
Special Wild Economic Animal and Plant Research
2015年
3期
61-64
,共4页
吴迪%李希珍%张旭%张楠淇%李平亚%王红
吳迪%李希珍%張旭%張楠淇%李平亞%王紅
오적%리희진%장욱%장남기%리평아%왕홍
愈伤灵胶囊%挥发油%气相色谱-质谱联用%化学成分
愈傷靈膠囊%揮髮油%氣相色譜-質譜聯用%化學成分
유상령효낭%휘발유%기상색보-질보련용%화학성분
Yushangling capsule%volatile%GC-MS%chemical costituents
采用气相色谱-质谱联用(GC-MS )法分析愈伤灵胶囊中的挥发油成分,为该制剂进一步研究及质量控制提供理论基础。采用《中国药典》一部(2010年版)附录XD方法提取愈伤灵胶囊的挥发油,应用GC-MS分析鉴定其化学成分,面积归一化法测定其相对含量。试验共检测出61个色谱峰,鉴定出其中的45个成分,占挥发油总数的95.22%,相对含量较多的化合物分别为龙脑(38.70%)和异龙脑(41.15%)。结果表明,愈伤灵胶囊中挥发油成分主要有龙脑和异龙脑等成分。
採用氣相色譜-質譜聯用(GC-MS )法分析愈傷靈膠囊中的揮髮油成分,為該製劑進一步研究及質量控製提供理論基礎。採用《中國藥典》一部(2010年版)附錄XD方法提取愈傷靈膠囊的揮髮油,應用GC-MS分析鑒定其化學成分,麵積歸一化法測定其相對含量。試驗共檢測齣61箇色譜峰,鑒定齣其中的45箇成分,佔揮髮油總數的95.22%,相對含量較多的化閤物分彆為龍腦(38.70%)和異龍腦(41.15%)。結果錶明,愈傷靈膠囊中揮髮油成分主要有龍腦和異龍腦等成分。
채용기상색보-질보련용(GC-MS )법분석유상령효낭중적휘발유성분,위해제제진일보연구급질량공제제공이론기출。채용《중국약전》일부(2010년판)부록XD방법제취유상령효낭적휘발유,응용GC-MS분석감정기화학성분,면적귀일화법측정기상대함량。시험공검측출61개색보봉,감정출기중적45개성분,점휘발유총수적95.22%,상대함량교다적화합물분별위용뇌(38.70%)화이용뇌(41.15%)。결과표명,유상령효낭중휘발유성분주요유용뇌화이용뇌등성분。
GC-MS was used to analyze the volatile oil components in Yushangling capsule in order to provide a theoretical basis for further re-search and quality control .The volatile oil components were extracted and isolated with steam distillation method according to ChP (2010) .The components were quantitatively determined with area normalization method and identified by GC -MS .Sixty-one compounds were detected .A-mong them ,only forty -five compounds were identified ,which accounted for 95.22% of total volatile composition .The main compounds were DL-Isoborneol (41.15% )and Borneol (38.70% ) ,respectively .The major volatile constituents of Yushangling capsule are DL -Isoborneol , Borneol etc .