中国基层医药
中國基層醫藥
중국기층의약
Chinese Journal of Primary Medicine and Pharmacy
2015年
20期
3107-3109
,共3页
宫颈糜烂%保妇康栓%聚甲酚磺醛
宮頸糜爛%保婦康栓%聚甲酚磺醛
궁경미란%보부강전%취갑분광철
Uterine cervical erosion%Baofukang suppository%Policresulen
目的：探讨保妇康栓联合聚甲酚磺醛治疗宫颈糜烂的临床疗效，并观察和分析其安全性，为临床治疗提供依据。方法选择宫颈糜烂患者268例，根据入院编号随机分为对照组和观察组，两组各134例，对照组在常规治疗基础上应用保妇康栓治疗；观察组应用保妇康栓及聚甲酚磺醛治疗。评估两组患者治疗效果、创面愈合时间，症状或体征改善状况，并观察两组患者阴道不良反应。结果观察组总有效率为88．81％（119／134），高于对照组的79．85％（107／134），差异有统计学意义（χ2＝9．87，P ＜0．05）；观察组患者创面愈合时间为（23．31±1．78）d，短于对照组的（27．58±1．96）d，差异有统计学意义（t ＝11．20，P ＜0．05）；观察组治疗后腰骶部酸痛、白带量多和脓性分泌物分别为9．70％（13／134）、5．94％（8／134）和3．73％（13／134），均低于对照组治疗后的14．93％（20／134）、12．69％（17／134）和11．94％（16／134），且两组治疗后均低于治疗前，差异有统计学意义（χ2＝9．96、9．81、10．12，均 P ＜0．05）；观察组和对照组治疗后接触性出血为分别为0．00％（0／134）和1．49％（2／134），均低于治疗前，差异有统计学意义（χ2＝11．30、10．06，均 P ＜0．05）；观察组阴道不良反应率为17．16％（23／134），对照组为17．91％（24／134），两组差异无统计学意义（P ＞0．05）。结论保妇康栓及聚甲酚磺醛治疗宫颈糜烂具有较好的临床疗效，能够缩短创面愈合时间，显著降低患者的症状或体征，并具有较高的安全性。
目的：探討保婦康栓聯閤聚甲酚磺醛治療宮頸糜爛的臨床療效，併觀察和分析其安全性，為臨床治療提供依據。方法選擇宮頸糜爛患者268例，根據入院編號隨機分為對照組和觀察組，兩組各134例，對照組在常規治療基礎上應用保婦康栓治療；觀察組應用保婦康栓及聚甲酚磺醛治療。評估兩組患者治療效果、創麵愈閤時間，癥狀或體徵改善狀況，併觀察兩組患者陰道不良反應。結果觀察組總有效率為88．81％（119／134），高于對照組的79．85％（107／134），差異有統計學意義（χ2＝9．87，P ＜0．05）；觀察組患者創麵愈閤時間為（23．31±1．78）d，短于對照組的（27．58±1．96）d，差異有統計學意義（t ＝11．20，P ＜0．05）；觀察組治療後腰骶部痠痛、白帶量多和膿性分泌物分彆為9．70％（13／134）、5．94％（8／134）和3．73％（13／134），均低于對照組治療後的14．93％（20／134）、12．69％（17／134）和11．94％（16／134），且兩組治療後均低于治療前，差異有統計學意義（χ2＝9．96、9．81、10．12，均 P ＜0．05）；觀察組和對照組治療後接觸性齣血為分彆為0．00％（0／134）和1．49％（2／134），均低于治療前，差異有統計學意義（χ2＝11．30、10．06，均 P ＜0．05）；觀察組陰道不良反應率為17．16％（23／134），對照組為17．91％（24／134），兩組差異無統計學意義（P ＞0．05）。結論保婦康栓及聚甲酚磺醛治療宮頸糜爛具有較好的臨床療效，能夠縮短創麵愈閤時間，顯著降低患者的癥狀或體徵，併具有較高的安全性。
목적：탐토보부강전연합취갑분광철치료궁경미란적림상료효，병관찰화분석기안전성，위림상치료제공의거。방법선택궁경미란환자268례，근거입원편호수궤분위대조조화관찰조，량조각134례，대조조재상규치료기출상응용보부강전치료；관찰조응용보부강전급취갑분광철치료。평고량조환자치료효과、창면유합시간，증상혹체정개선상황，병관찰량조환자음도불량반응。결과관찰조총유효솔위88．81％（119／134），고우대조조적79．85％（107／134），차이유통계학의의（χ2＝9．87，P ＜0．05）；관찰조환자창면유합시간위（23．31±1．78）d，단우대조조적（27．58±1．96）d，차이유통계학의의（t ＝11．20，P ＜0．05）；관찰조치료후요저부산통、백대량다화농성분비물분별위9．70％（13／134）、5．94％（8／134）화3．73％（13／134），균저우대조조치료후적14．93％（20／134）、12．69％（17／134）화11．94％（16／134），차량조치료후균저우치료전，차이유통계학의의（χ2＝9．96、9．81、10．12，균 P ＜0．05）；관찰조화대조조치료후접촉성출혈위분별위0．00％（0／134）화1．49％（2／134），균저우치료전，차이유통계학의의（χ2＝11．30、10．06，균 P ＜0．05）；관찰조음도불량반응솔위17．16％（23／134），대조조위17．91％（24／134），량조차이무통계학의의（P ＞0．05）。결론보부강전급취갑분광철치료궁경미란구유교호적림상료효，능구축단창면유합시간，현저강저환자적증상혹체정，병구유교고적안전성。
Objective To explore the clinical efficacy of Baofukang suppository and policresulen in the treat-ment of cervical erosion,and to observe and analyze the safety,thus to provide the basis for clinical treatment.Methods 268 patients with cervical erosion were selected,they were randomly divided into the control group and the observation group,134 cases in each group.The control group was treated with Baofukang suppository on the basis of conventional treatment.The observation group received Baofukang suppository and policresulen treatment.To assess the treatment effect of the two groups,and the wound healing time,improvement of the symptoms or signs and the vaginal adverse reactions were observed.Results The total effective rate of the observation group was 88.81% (119 /134),which was higher than that of the control group 79.85% (107 /134),the difference was statistically significant (χ2 =9.87, P <0.05).The wound healing time of the observation group was (23.31 ±1.78)d,which was shorter than that of the control group (27.58 ±1.96)d,the difference was statistically significant (t =11.20,P <0.05).The incidence rates of lumbosacral pain,leucorrhea and purulent secretions of the observation group after treatment were 9.70%(13 /134),5.94% (8 /134)and 3.73% (13 /134),which were lower than those in the control group after treatment [14.93%(20 /134),12.69% (17 /134)and 11.94% (16 /134)],and after treatment two groups were lower than those before treatment,there were statistically significant differences (χ2 =9.96,9.81,10.12,all P <0.05).After treatment,the contact bleeding of the observation group and the control group were 0.00% (0 /134)and 1.49%(2 /134),which were lower than those before treatment,the differences were statistically significant (χ2 =11.30,10.06, all P <0.05).The incidence rate of vagina adverse reaction of the observation groups was 17.16% (23 /134),that of the control group was 17.91% (24 /134),there was no statistically significant difference (P >0.05).Conclusion Baofukang suppository combined with policresulen has better clinical curative effect in the treatment of cervical ero-sion,which can shorten the wound healing time,reduce symptoms or signs of patients,and has high security.
