CAJ | 학술논문

以从制药废液中回收四氢呋喃为例,详细研究萃取精馏过程的Aspen Plus模拟和优化.通过实验与热力学模型预测的对比确定NRTL方程能更准确地描述THF-水-DMSO三元混合物系气液相平衡;分析THF-水-DMSO三元混合物系剩余曲线说明DMSO是萃取精馏分离该共沸物系的可行萃取剂;设计萃取精馏分离工艺流程并以萃取精馏塔为例,运用灵敏度分析对过程进行优化,结果表明:200 kmol/h进料量的常压萃取精馏,塔板数22,萃取剂和原料液分别在第4和第18块板进料,回流比 1. 0,溶剂比 0. 45 的条件下可得到纯度高于 99. 85 %的 THF,回收率高于99. 5 %.
이종제약폐액중회수사경부남위례,상세연구췌취정류과정적Aspen Plus모의화우화.통과실험여열역학모형예측적대비학정NRTL방정능경준학지묘술THF-수-DMSO삼원혼합물계기액상평형;분석THF-수-DMSO삼원혼합물계잉여곡선설명DMSO시췌취정류분리해공비물계적가행췌취제;설계췌취정류분리공예류정병이췌취정류탑위례,운용령민도분석대과정진행우화,결과표명:200 kmol/h진료량적상압췌취정류,탑판수22,췌취제화원료액분별재제4화제18괴판진료,회류비 1. 0,용제비 0. 45 적조건하가득도순도고우 99. 85 %적 THF,회수솔고우99. 5 %.
In this paper,we take the instance of recovering THF from pharmaceutical wastes to investi-gate the simulation and optimization of extractive distillation process using Aspen Plus. Firstly,the contrast of experimental data with thermodynamic model prediction indicates that NRTL model describes the VLE behavior of THF-water-DMSO system more accurately. Analyzing the residue curve map of THF-water-DMSO system shows that DMSO is a feasible entrainer. The extractive distillation process is established and optimized taking extraction distillation column as an instance through sensitivity analysis. The influ-ences of process parameters are explored. The results show that while the feed rate is set as 200 kmol/h under atmospheric pressure,stage number 22,entrainer and the binary mixture fed on 4th and 18th stage respectively, reflux ratio 1. 0,solvent ratio 0. 45 is optimized condition under which we can obtain THF purer than 99. 85 %,and the recovery of THF can be higher than 99. 5 % meeting the requirements of industrial design.