CAJ | 학술논문

目的：探索清洁手术围手术期预防性应用抗菌药物的情况及抗菌药物监管的有效途径，促进抗菌药物的合理应用。方法采用回顾性横断面调查方法，对该院2009年9月（抗菌药物专项整治活动前）和2012年8月（抗菌药物专项整治活动后）乳腺科、普通外科、骨科清洁手术围手术期预防性应用抗菌药物情况进行统计分析。结果通过加强医院监管，清洁手术围手术期抗菌药物使用率从2008年8月的99．02％下降至2012年8月22．33％；选用药物品种合理率从61．11％上升至91．76％，术前0．5～2h内用药率从37．78％上升至95．29％；平均术后用药时间从4．03d缩短至不超过24 h ；用药合理率从21．11％升高至84．44％。结论通过进行围手术期抗菌药物应用严格监管，可以明显提高抗菌药物应用的合理性。
목적：탐색청길수술위수술기예방성응용항균약물적정황급항균약물감관적유효도경，촉진항균약물적합리응용。방법채용회고성횡단면조사방법，대해원2009년9월（항균약물전항정치활동전）화2012년8월（항균약물전항정치활동후）유선과、보통외과、골과청길수술위수술기예방성응용항균약물정황진행통계분석。결과통과가강의원감관，청길수술위수술기항균약물사용솔종2008년8월적99．02％하강지2012년8월22．33％；선용약물품충합리솔종61．11％상승지91．76％，술전0．5～2h내용약솔종37．78％상승지95．29％；평균술후용약시간종4．03d축단지불초과24 h ；용약합리솔종21．11％승고지84．44％。결론통과진행위수술기항균약물응용엄격감관，가이명현제고항균약물응용적합이성。
Objective To study antimicrobial prophylactic usage in clean surgical operations and investi‐gate management of antimicrobial usage ,so as to promote rational use of antimicrobial angents .Methods Cross‐sectional study was carried out on the rationality of antimicrobial application in patients at breast surgery ,general surgery and orthopedics surgery depanments in August ,2009 (before Special rectification activities of antimicrobial agents) and August ,2012(after Special rectification activities of antimicrobial a‐gents) .Results Through performing management of antimicrobial application agents ,preoperative antimi‐crobial prophylactic application rate in patients undergoing aseptic operation decreased from 99 .02% in au‐gust ,2009 to 22 .33% in august ,2012 ;the rate of using rational kind antimicrobial agents increased from 61 . 11% to 91 .76% ,0 .5‐2h of antimicrobial agents used rate before the operation increased from 37 .78% to 95 .29% ;the time of using antimicrobial agents after medication decreased from 4 .03 days to less than 24 hours ,Rational application rate increased from 21 .11% to84 .44% .Conclusion Through education of ra‐tional use of antimicrobial agents ,Reinforcing management of antimicrobials can improve the rationality of prophylactic use .