中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
10期
1386-1389,1390
,共5页
药品不良反应%抗菌药物%静脉滴注%合理用药
藥品不良反應%抗菌藥物%靜脈滴註%閤理用藥
약품불량반응%항균약물%정맥적주%합리용약
Adverse drug reaction%Antibacterial drugs%Intravenous drip%Rational of drug use
目的：了解厦门市第三医院（以下简称“我院”）药品不良反应（ adverse drug reaction，ADR）发生的特点，为临床安全用药提供参考。方法：对我院2013年收集的384例ADR报告，按患者性别与年龄、药品种类、给药途径、ADR累及器官和（或）系统及其临床表现、报告人职业、ADR的类型及结果等进行统计分析。结果：384例ADR报告涉及17类143种药品，其中，发生ADR的抗菌药物品种数和例次数最多，分别为37种（占25.87％）、123例次（占合计450例次的27.33％）；发生ADR的给药途径以静脉滴注为主，共208例（占54.17％）；ADR的临床表现以皮肤及其附件损害为主，共149例次（占合计480例次的31.04％）；医师报告的ADR病例数最多，共341例（占88.80％）。结论：应合理用药并重视ADR监测，以避免或减少ADR的重复发生。
目的：瞭解廈門市第三醫院（以下簡稱“我院”）藥品不良反應（ adverse drug reaction，ADR）髮生的特點，為臨床安全用藥提供參攷。方法：對我院2013年收集的384例ADR報告，按患者性彆與年齡、藥品種類、給藥途徑、ADR纍及器官和（或）繫統及其臨床錶現、報告人職業、ADR的類型及結果等進行統計分析。結果：384例ADR報告涉及17類143種藥品，其中，髮生ADR的抗菌藥物品種數和例次數最多，分彆為37種（佔25.87％）、123例次（佔閤計450例次的27.33％）；髮生ADR的給藥途徑以靜脈滴註為主，共208例（佔54.17％）；ADR的臨床錶現以皮膚及其附件損害為主，共149例次（佔閤計480例次的31.04％）；醫師報告的ADR病例數最多，共341例（佔88.80％）。結論：應閤理用藥併重視ADR鑑測，以避免或減少ADR的重複髮生。
목적：료해하문시제삼의원（이하간칭“아원”）약품불량반응（ adverse drug reaction，ADR）발생적특점，위림상안전용약제공삼고。방법：대아원2013년수집적384례ADR보고，안환자성별여년령、약품충류、급약도경、ADR루급기관화（혹）계통급기림상표현、보고인직업、ADR적류형급결과등진행통계분석。결과：384례ADR보고섭급17류143충약품，기중，발생ADR적항균약물품충수화례차수최다，분별위37충（점25.87％）、123례차（점합계450례차적27.33％）；발생ADR적급약도경이정맥적주위주，공208례（점54.17％）；ADR적림상표현이피부급기부건손해위주，공149례차（점합계480례차적31.04％）；의사보고적ADR병례수최다，공341례（점88.80％）。결론：응합리용약병중시ADR감측，이피면혹감소ADR적중복발생。
OBJECTIVE:To investigate the characteristics of adverse drug reaction ( ADR ) reports in the Third Hospital of Xiamen( hereinafter referred to as “our hospital”) , and to provided reference for the clinical medication safety.METHODS:384 cases of ADR reports were collected in our hospital, statistical analysis was conducted on the patients'gender, age, varieties of drugs, route of administration and ADR involved organs and( or) systems and clinical manifestations, report stuff, types and outcomes of ADR, etc.RESULTS:384 cases of ADR reports involving 17 types and 143 varieties of drugs, among which the main parts were varieties and cases of antibacterial drugs that induced ADR, respectively were 37 varieties(25.87%) and 123 cases(accounting for 27.33%of 450 cases).The main route of administration that induced ADR were intravenous drip, totally 208 cases(54.17%);the clinical manifestation of ADR manifested as skin and its accessories damage, totally 149 cases(accounting for 31.04% for 480 cases);the ADR cases reported by doctors were the most, totally 341 cases ( 88.80%) .CONCLUSIONS:It is necessary to promote the rational drug use and strengthen ADR monitoring so as to avoid or reduce the incidence of ADR.
