中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
10期
1302-1303
,共2页
李宁%姜一平%施文科%邓锡岳
李寧%薑一平%施文科%鄧錫嶽
리저%강일평%시문과%산석악
地佐辛注射液%芬太尼注射液%自控镇痛
地佐辛註射液%芬太尼註射液%自控鎮痛
지좌신주사액%분태니주사액%자공진통
Dezocine intravenous fluid%Fentanyl injection%Patient-controlled analgesia
目的：探讨应用地佐辛注射液静脉注射进行术后自控镇痛的临床效果。方法：将180例肛肠外科老年患者作为研究对象，按照随机数字表法分为观察组和对照组各90例，对照组患者应用芬太尼注射液，观察组患者应用地佐辛注射液，观察2组患者2、6、12、24、48 h的视觉模拟评分（ visualanaloguescale，VAS）、Ramsay评分，比较2组患者的不良反应发生情况。结果：2组患者各时间段VAS评分均在2分以下，且呈逐渐降低趋势；Ramsay评分均在2～3分范围内，2组的差异无统计学意义（ P＞0.05）；观察组患者的不良反应率为7.78％（7／90），显著低于对照组的18.89％（17／90），2组的差异有统计学意义（P＜0.05）。结论：患者术后自控镇痛应用地佐辛注射液效果确切，安全性高，值得临床推广。
目的：探討應用地佐辛註射液靜脈註射進行術後自控鎮痛的臨床效果。方法：將180例肛腸外科老年患者作為研究對象，按照隨機數字錶法分為觀察組和對照組各90例，對照組患者應用芬太尼註射液，觀察組患者應用地佐辛註射液，觀察2組患者2、6、12、24、48 h的視覺模擬評分（ visualanaloguescale，VAS）、Ramsay評分，比較2組患者的不良反應髮生情況。結果：2組患者各時間段VAS評分均在2分以下，且呈逐漸降低趨勢；Ramsay評分均在2～3分範圍內，2組的差異無統計學意義（ P＞0.05）；觀察組患者的不良反應率為7.78％（7／90），顯著低于對照組的18.89％（17／90），2組的差異有統計學意義（P＜0.05）。結論：患者術後自控鎮痛應用地佐辛註射液效果確切，安全性高，值得臨床推廣。
목적：탐토응용지좌신주사액정맥주사진행술후자공진통적림상효과。방법：장180례항장외과노년환자작위연구대상，안조수궤수자표법분위관찰조화대조조각90례，대조조환자응용분태니주사액，관찰조환자응용지좌신주사액，관찰2조환자2、6、12、24、48 h적시각모의평분（ visualanaloguescale，VAS）、Ramsay평분，비교2조환자적불량반응발생정황。결과：2조환자각시간단VAS평분균재2분이하，차정축점강저추세；Ramsay평분균재2～3분범위내，2조적차이무통계학의의（ P＞0.05）；관찰조환자적불량반응솔위7.78％（7／90），현저저우대조조적18.89％（17／90），2조적차이유통계학의의（P＜0.05）。결론：환자술후자공진통응용지좌신주사액효과학절，안전성고，치득림상추엄。
OBJECTIVE:To probe into the clinical efficacy of dezocine intravenous fluid in treatment of postoperative patient-controlled analgesia.METHODS: 180 cases of elderly patients in anal-colorectal surgery were selected to be divided into observation group and control group via random number table, with 90 cases in each group. The control group received fentanyl injection, and the observation group received dezocine injection; the visualanaloguescale( VAS) scores, Ramsay scores of 2 h,6 h,12 h,24 h,48 h in two group of patients were observed, and the adverse reactions of two group of patients were compared.RESULTS: The VAS scores in two groups with different time points were below 2 , and showed a decreasing trend with time;the Ramsay scores were at the range of 2-3, there were no statistically significant difference between two groups ( P>0.05) .The rate of adverse reactions in observation group were [ 7.78%( 7/90 ) ] , significantly lower than that in control group [ 18.89%( 17/90 ) ] , with statistically significant difference ( P<0.05 ) .CONCLUSIONS:Dezocine intravenous fluid in treatment of postoperative patient-controlled analgesia has a good clinical efficacy and high security, which is worthy of clinical promotion.
