中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
10期
1293-1295
,共3页
慢性咽炎%富马酸阿奇霉素%清热散结片%临床疗效
慢性嚥炎%富馬痠阿奇黴素%清熱散結片%臨床療效
만성인염%부마산아기매소%청열산결편%림상료효
Chronic pharyngitis%Azithromycin fumarate tablets%Qingresanjie tablets%Clinical efficacy
目的：探讨清热散结片联合富马酸阿奇霉素治疗慢性咽炎的效果。方法：选取慢性咽炎患者140例作为研究对象，采用随机数字表法将患者分为对照组和观察组各70例，对照组患者予以富马酸阿奇霉素片，观察组患者在对照组基础上予以清热散结片，记录2组患者咳嗽、咽喉痛及声嘶消失时间，行临床症状评分，评估临床疗效并记录不良反应发生情况。结果：观察组患者总有效率为92.86％（65／70），显著高于对照组的75.71％（53／70），差异有统计学意义（P＜0.05）；观察组患者治疗后声嘶、咽喉痛及咳嗽消失时间为（2.26±0.38）、（3.49±0.47）、（4.21±0.43）d，均明显短于对照组的（3.59±0.44）、（5.01±0.35）、（5.89±0.53）d，差异有统计学意义（P＜0.05）；观察组患者治疗后咽部疼痛、异物感、咽干、咳痰评分为（0.94±0.24）、（1.03±0.30）、（0.84±0.36）、（0.75±0.28）分，均显著低于对照组的（1.59±0.38）、（1.81±0.27）、（1.35±0.41）、（1.44±0.32）分，差异有统计学意义（ P＜0.05）。结论：清热散结片联合富马酸阿奇霉素治疗慢性咽炎能够改善患者症状，提高临床疗效，无明显不良反应，值得临床推广。
目的：探討清熱散結片聯閤富馬痠阿奇黴素治療慢性嚥炎的效果。方法：選取慢性嚥炎患者140例作為研究對象，採用隨機數字錶法將患者分為對照組和觀察組各70例，對照組患者予以富馬痠阿奇黴素片，觀察組患者在對照組基礎上予以清熱散結片，記錄2組患者咳嗽、嚥喉痛及聲嘶消失時間，行臨床癥狀評分，評估臨床療效併記錄不良反應髮生情況。結果：觀察組患者總有效率為92.86％（65／70），顯著高于對照組的75.71％（53／70），差異有統計學意義（P＜0.05）；觀察組患者治療後聲嘶、嚥喉痛及咳嗽消失時間為（2.26±0.38）、（3.49±0.47）、（4.21±0.43）d，均明顯短于對照組的（3.59±0.44）、（5.01±0.35）、（5.89±0.53）d，差異有統計學意義（P＜0.05）；觀察組患者治療後嚥部疼痛、異物感、嚥榦、咳痰評分為（0.94±0.24）、（1.03±0.30）、（0.84±0.36）、（0.75±0.28）分，均顯著低于對照組的（1.59±0.38）、（1.81±0.27）、（1.35±0.41）、（1.44±0.32）分，差異有統計學意義（ P＜0.05）。結論：清熱散結片聯閤富馬痠阿奇黴素治療慢性嚥炎能夠改善患者癥狀，提高臨床療效，無明顯不良反應，值得臨床推廣。
목적：탐토청열산결편연합부마산아기매소치료만성인염적효과。방법：선취만성인염환자140례작위연구대상，채용수궤수자표법장환자분위대조조화관찰조각70례，대조조환자여이부마산아기매소편，관찰조환자재대조조기출상여이청열산결편，기록2조환자해수、인후통급성시소실시간，행림상증상평분，평고림상료효병기록불량반응발생정황。결과：관찰조환자총유효솔위92.86％（65／70），현저고우대조조적75.71％（53／70），차이유통계학의의（P＜0.05）；관찰조환자치료후성시、인후통급해수소실시간위（2.26±0.38）、（3.49±0.47）、（4.21±0.43）d，균명현단우대조조적（3.59±0.44）、（5.01±0.35）、（5.89±0.53）d，차이유통계학의의（P＜0.05）；관찰조환자치료후인부동통、이물감、인간、해담평분위（0.94±0.24）、（1.03±0.30）、（0.84±0.36）、（0.75±0.28）분，균현저저우대조조적（1.59±0.38）、（1.81±0.27）、（1.35±0.41）、（1.44±0.32）분，차이유통계학의의（ P＜0.05）。결론：청열산결편연합부마산아기매소치료만성인염능구개선환자증상，제고림상료효，무명현불량반응，치득림상추엄。
OBJECTIVE:To probe into the efficacy of Qingresanjie tablets combined with Azithromycin fumarate tablets in treatment of chronic pharyngitis.METHODS:140 cases of patients with chronic pharyngitis admitted into the hospital were selected as the research object.According to the random number table, the patients were divided into the observation group and the control group each 70 cases.The control group were treated with Azithromycin fumarate tablets while the observation group received Qingresanjie tablets on the basis of the control group.The disappearance time of coughing, throat pain and hoarseness of the patients in two groups were recorded.The clinical symptoms were scored to evaluate the clinical efficacy and the adverse reactions were recorded.RESULTS:The total effective rate in the observation group was[92.86%(65/70)], which was significantly higher than that in the control group [75.71%(53/70)], the difference was statistically significant (P<0.05).The disappearance time of hoarseness, throat pain and coughing of the observation group after the treatment were respectively (2.26 ±0.38) d, (3.49 ±0.47) d and (4.21 ±0.43) d, which was shorter than those of the control group(3.59 ±0.44) d,(5.01 ±0.35) d and (5.89 ± 0.53) d, the difference was statistically significant (P<0.05).The scores of throat pain, foreign body sensation, dry throat and expectoration of the observation group after the treatment were respectively (0.94 ±0.24) scores, (1.03 ± 0.30) scores, (0.84 ±0.36) scores and (0.75 ±0.28) scores which were significantly lower than those of the control group (1.59 ±0.38) scores,(1.81 ±0.27) scores,(1.35 ±0.41) scores and (1.44 ±0.32) scores, the difference was statistically significant (P<0.05).CONCLUSIONS:Qingresanjie tablets combined with Azithromycin fumarate tablets in treatment of chronic pharyngitis can relief the symptoms of patients and improve the clinical efficacy with few adverse reactions.It is worthy of clinical promotion.
