中国综合临床
中國綜閤臨床
중국종합림상
Clinical Medicine of China
2015年
10期
884-886
,共3页
原发性肝癌%化疗栓塞%个体化治疗%综合治疗
原髮性肝癌%化療栓塞%箇體化治療%綜閤治療
원발성간암%화료전새%개체화치료%종합치료
Primary liver cancer%Transcatheter arterial chemoembolization%Individual treatment%Comprehensive treatment
目的 探讨肝动脉化疗栓塞术(TACE)治疗不能手术切除原发性肝癌的具体方法.方法 回顾性分析1991年1月至2010年3月TACE治疗312例不能手术切除原发性肝癌患者的临床一般资料、治疗方法及随访资料.312例不能手术原发性肝癌患者,依据门静脉造影门静脉通畅情况、肝动脉造影病变范围、血供类型和聚碘程度、全身状况,施以不同剂量及方法的TACE及免疫和营养支持治疗,部分患者配合肝癌冷冻、射频或无水乙醇注射治疗.结果 随访287例患者,随访率92％;42例因病变范围缩小或局限,行二期手术探查,其中34例行肝切除手术,8例行肝癌冷冻术.全组患者1、3、5年生存率分别为87.6％、33.1％、13.2％.结论 TACE用于不能手术切除原发性肝癌的治疗,治疗方案应个体化,辅以综合治疗,一旦肝癌缩小有手术切除指征,应尽早手术切除.
目的 探討肝動脈化療栓塞術(TACE)治療不能手術切除原髮性肝癌的具體方法.方法 迴顧性分析1991年1月至2010年3月TACE治療312例不能手術切除原髮性肝癌患者的臨床一般資料、治療方法及隨訪資料.312例不能手術原髮性肝癌患者,依據門靜脈造影門靜脈通暢情況、肝動脈造影病變範圍、血供類型和聚碘程度、全身狀況,施以不同劑量及方法的TACE及免疫和營養支持治療,部分患者配閤肝癌冷凍、射頻或無水乙醇註射治療.結果 隨訪287例患者,隨訪率92％;42例因病變範圍縮小或跼限,行二期手術探查,其中34例行肝切除手術,8例行肝癌冷凍術.全組患者1、3、5年生存率分彆為87.6％、33.1％、13.2％.結論 TACE用于不能手術切除原髮性肝癌的治療,治療方案應箇體化,輔以綜閤治療,一旦肝癌縮小有手術切除指徵,應儘早手術切除.
목적 탐토간동맥화료전새술(TACE)치료불능수술절제원발성간암적구체방법.방법 회고성분석1991년1월지2010년3월TACE치료312례불능수술절제원발성간암환자적림상일반자료、치료방법급수방자료.312례불능수술원발성간암환자,의거문정맥조영문정맥통창정황、간동맥조영병변범위、혈공류형화취전정도、전신상황,시이불동제량급방법적TACE급면역화영양지지치료,부분환자배합간암냉동、사빈혹무수을순주사치료.결과 수방287례환자,수방솔92％;42례인병변범위축소혹국한,행이기수술탐사,기중34례행간절제수술,8례행간암냉동술.전조환자1、3、5년생존솔분별위87.6％、33.1％、13.2％.결론 TACE용우불능수술절제원발성간암적치료,치료방안응개체화,보이종합치료,일단간암축소유수술절제지정,응진조수술절제.
Objective To investigate the therapeutic measures of unresectable primary liver cancer (PLC) with transcatheter arterial chemoembolization(TACE).Methods The clinical data,treatment measures and followed up data of 312 patients with unresectable primary liver cancer from January 1991 to March 2010 were analyzed retrospectively.Of these 312 patients, different dosages, measures of transcatheter arterial chemoembolization together with immunotherapy and nutritional support treatments were given to the patients according to their own statements, including the patency of portal vein (evaluated by portography), the range, blood supply and lipiodol concentration of the lesions (evaluated by hepatic arteriography), and the systemic conditions.Some of these patients also accepted cryotherapy, radio frequency ablation (RFA), percutaneous ethanol injection therapy.Results Two hundred and eighty-seven patients were followed up (92％).Forty-two cases accepted the two-stage operation as the lesions were localized or reduced.In these 42 patients, 34 cases accepted the hepatectomy, 8 cases accepted the cryotherapy.The 1,3 and 5 year survival rate of all patients were 87.6％, 33.1％ and 13.2％.Conclusion TACE for unresectable primary liver cancer should be used individually and comprehensivly.Surgical treatment should be taken once the lesions can be resected.
