CAJ | 학술논문

心型脂肪酸结合蛋白（ H－FABP）是评价心肌组织损伤的一种更为敏感的新型生物标志物，其能从损伤的心肌组织中快速释放到血液中。随着对H－FABP越来越深入的研究，研究者发现其也在脑、骨骼肌、肺、肾、肾上腺和乳腺等组织中表达，故其在临床中的应用（如早期诊断、危险分层、预后评估等）越来越广泛。目前的研究主要集中在成人疾病中，在儿科疾病中报道不多。
심형지방산결합단백（ H－FABP）시평개심기조직손상적일충경위민감적신형생물표지물，기능종손상적심기조직중쾌속석방도혈액중。수착대H－FABP월래월심입적연구，연구자발현기야재뇌、골격기、폐、신、신상선화유선등조직중표체，고기재림상중적응용（여조기진단、위험분층、예후평고등）월래월엄범。목전적연구주요집중재성인질병중，재인과질병중보도불다。
Heart-type fatty acid binding protein ( H-FABP) is one of the promising biological markers for the evaluation of myocardial injury.H-FABP is known to be rapid released from injured myocardium into the blood.With the progress of the study, it is discovered that H-FABP is also expressed in brain, skeletal muscle,lung,kidney,adrenal,mammary gland and so on.Because it is an effective marker for early diagno-sis,risk stratification,and assessing prognosis,it′s more and more widely applied in clinical.At present,the study of H-FABP is focused on adult disease,but rarely reported in pediatric disease.