世界最新医学信息文摘(连续型电子期刊)
世界最新醫學信息文摘(連續型電子期刊)
세계최신의학신식문적(련속형전자기간)
World Latest Medicine Information
2015年
58期
30-31
,共2页
全身麻醉%肺癌根治术%免疫功能
全身痳醉%肺癌根治術%免疫功能
전신마취%폐암근치술%면역공능
general anesthesia%lung cancer radical operation%immune function
目的:分析全身麻醉复合硬膜外阻滞麻醉对肺癌根治术患者免疫功能的影响。方法选择我院2013年1月到2015年1月收治的80例肺癌患者作为研究对象,采用盲法随机分为观察组与对照组,每组40例,观察组患者采用全身麻醉,对照组患者采用全身麻醉复合硬膜外阻滞麻醉,观察两组术后患者恢复自主呼吸时间、轻呼睁眼时间、拔管时间、术后2d与第7d外周血CD4+T、CD8+T、自然杀伤(NK)细胞水平。结果结果显示观察组的患者恢复自主呼吸时间、轻呼睁眼时间以及拔管时间均短于对照组,差异具有统计学意义(P<0.05);术后第2d观察组与对照组CD4+T、CD8+T、NK细胞水平明显低于术前,差异具有统计学意义(P<0.05);术后第2d观察组的CD4+T、CD8+T、NK细胞水平明显高于对照组,差异具有统计学意义(P<0.05);术后第7d观察组NK细胞水平明显高于对照组,差异具有统计学意义(P<0.05)。结论全身麻醉复合硬膜外阻滞麻醉对患者的细胞免疫功能影响较小,患者术后恢复快,值得在临床上推广。
目的:分析全身痳醉複閤硬膜外阻滯痳醉對肺癌根治術患者免疫功能的影響。方法選擇我院2013年1月到2015年1月收治的80例肺癌患者作為研究對象,採用盲法隨機分為觀察組與對照組,每組40例,觀察組患者採用全身痳醉,對照組患者採用全身痳醉複閤硬膜外阻滯痳醉,觀察兩組術後患者恢複自主呼吸時間、輕呼睜眼時間、拔管時間、術後2d與第7d外週血CD4+T、CD8+T、自然殺傷(NK)細胞水平。結果結果顯示觀察組的患者恢複自主呼吸時間、輕呼睜眼時間以及拔管時間均短于對照組,差異具有統計學意義(P<0.05);術後第2d觀察組與對照組CD4+T、CD8+T、NK細胞水平明顯低于術前,差異具有統計學意義(P<0.05);術後第2d觀察組的CD4+T、CD8+T、NK細胞水平明顯高于對照組,差異具有統計學意義(P<0.05);術後第7d觀察組NK細胞水平明顯高于對照組,差異具有統計學意義(P<0.05)。結論全身痳醉複閤硬膜外阻滯痳醉對患者的細胞免疫功能影響較小,患者術後恢複快,值得在臨床上推廣。
목적:분석전신마취복합경막외조체마취대폐암근치술환자면역공능적영향。방법선택아원2013년1월도2015년1월수치적80례폐암환자작위연구대상,채용맹법수궤분위관찰조여대조조,매조40례,관찰조환자채용전신마취,대조조환자채용전신마취복합경막외조체마취,관찰량조술후환자회복자주호흡시간、경호정안시간、발관시간、술후2d여제7d외주혈CD4+T、CD8+T、자연살상(NK)세포수평。결과결과현시관찰조적환자회복자주호흡시간、경호정안시간이급발관시간균단우대조조,차이구유통계학의의(P<0.05);술후제2d관찰조여대조조CD4+T、CD8+T、NK세포수평명현저우술전,차이구유통계학의의(P<0.05);술후제2d관찰조적CD4+T、CD8+T、NK세포수평명현고우대조조,차이구유통계학의의(P<0.05);술후제7d관찰조NK세포수평명현고우대조조,차이구유통계학의의(P<0.05)。결론전신마취복합경막외조체마취대환자적세포면역공능영향교소,환자술후회복쾌,치득재림상상추엄。
Objective: To analyze the effect of general anesthesia combined with epidural block anesthesia on the immune function of patients with lung cancer.Methods: Patients in the observation group were given general anesthesia, patients in the control group with general anesthesia combined with epidural block anesthesia observed after operation in two groups of patients recovered spontaneous breathing time, whisper time to eye opening, extubation time, postoperative 2D and 7d week CD4 +, CD8 + T and natural killer (NK) at the cellular level.Results: The results showed that the patients in the observation group, the recovery time to spontaneous breathing, whisper eyes time and extubation time were shorter than the control group, with statistically significant difference (P <0.05); after the 2D observation group and the control group of CD4 + T, the level of CD8 + T cells and NK cells was significantly lower than that of the preoperative, the difference has statistical significance (P < 0.05).Conclusion: The effect of combined epidural block anesthesia on cellular immune function in patients with general anesthesia is small, and the recovery of patients after operation is fast, and it is worthy to be popularized in clinic.