世界最新医学信息文摘（连续型电子期刊）
世界最新醫學信息文摘（連續型電子期刊）
세계최신의학신식문적（련속형전자기간）
World Latest Medicine Information
2015年
58期
27-28
,共2页
眼前节疾病%抗VEGF%围手术期%雷珠单抗
眼前節疾病%抗VEGF%圍手術期%雷珠單抗
안전절질병%항VEGF%위수술기%뢰주단항
anterior segment disease%anti VEGF%Perioperative
目的：探讨抗VEGF药物在眼前节疾病围术期中的应用效果。方法根据治疗方法的不同，将90例眼前节疾病患者分为观察组和对照组（每组45例），两组患者均行手术治疗，观察组在此基础上加用抗VEGF药物，比较两组患者的临床疗效。结果治疗后，两组的眼压水平均较治疗前显著降低，且观察组治疗后7d、30d、90d的眼压水平均显著低于对照组，P<0.05。观察组治疗有效率为98.0%，显著高于对照组的88.46%，P<0.05。结论对行手术治疗的眼前节疾病患者应用抗VEGF药物，能够有效抑制视网膜及虹膜上新生血管的生成与增殖，提高手术疗效。
目的：探討抗VEGF藥物在眼前節疾病圍術期中的應用效果。方法根據治療方法的不同，將90例眼前節疾病患者分為觀察組和對照組（每組45例），兩組患者均行手術治療，觀察組在此基礎上加用抗VEGF藥物，比較兩組患者的臨床療效。結果治療後，兩組的眼壓水平均較治療前顯著降低，且觀察組治療後7d、30d、90d的眼壓水平均顯著低于對照組，P<0.05。觀察組治療有效率為98.0%，顯著高于對照組的88.46%，P<0.05。結論對行手術治療的眼前節疾病患者應用抗VEGF藥物，能夠有效抑製視網膜及虹膜上新生血管的生成與增殖，提高手術療效。
목적：탐토항VEGF약물재안전절질병위술기중적응용효과。방법근거치료방법적불동，장90례안전절질병환자분위관찰조화대조조（매조45례），량조환자균행수술치료，관찰조재차기출상가용항VEGF약물，비교량조환자적림상료효。결과치료후，량조적안압수평균교치료전현저강저，차관찰조치료후7d、30d、90d적안압수평균현저저우대조조，P<0.05。관찰조치료유효솔위98.0%，현저고우대조조적88.46%，P<0.05。결론대행수술치료적안전절질병환자응용항VEGF약물，능구유효억제시망막급홍막상신생혈관적생성여증식，제고수술료효。
Objective: To investigate the effect of anti VEGF drugs in the perioperative period of the patients with anterior segment disease.Methods: According to different treatment methods, 90 patients with anterior segment disease were divided into observation group and control group (45 cases). The patients in the two groups were treated by operation, and the observation group was treated with anti VEGF drugs, and the clinical efficacy of the two groups were compared.Results: After treatment, the two groups of IOP were significantly lower than before treatment, and the observation group after treatment, 30d, 90d, 7d were significantly lower than the control group,P<0.05. The effective rate of the observation group was 98%, significantly higher than the control group of 88.46%, P<0.05.Conclusion: The use of anti VEGF drugs in the treatment of patients with anterior segment disease can effectively inhibit the generation and proliferation of new blood vessels in the retina and iris.
