医学综述
醫學綜述
의학종술
Medical Recapitulate
2015年
18期
3421-3423
,共3页
冠心病%冠状动脉病变%SYNTAX评分%相关因素
冠心病%冠狀動脈病變%SYNTAX評分%相關因素
관심병%관상동맥병변%SYNTAX평분%상관인소
Coronary heart disease%Coronary artery lesions%SYNTAX score%Related factors
目的:探讨冠状动脉粥样硬化性心脏病(冠心病)患者冠状动脉病变SYNTAX评分与冠心病易患因素的相关性。方法选取2011年4月至2013年4月驻马店市第一人民医院收治的117例冠心病患者为研究对象,依据患者SYNTAX评分分为低危组(31例)、中危组(37例)和高危组(49例)。采用Spearman秩相关分析和多元逐步回归分析探讨冠状动脉病变SYNTAX评分与冠心病易患因素的相关性。结果高危组患者吸烟率、糖尿病率、高血压率、三酰甘油、同型半胱氨酸水平均显著高于中危组[69.4%(34/49)比56.8%(21/37),48.9%(24/49)比35.1%(13/37),46.9%(23/49)比32.4%(12/37),(2.0±1.0) mmol/L比(1.8±0.9) mmol/L,(37±9)μmol/L比(24±8)μmol/L]、低危组[48.4%(15/31),22.6%(7/31),12.9%(4/31),(1.8±0.9) mmol/L,(16±7)μmol/L],差异有统计学意义(P<0.05),且中危组患者上述指标均高于低危组,差异有统计学意义( P<0.05)。多元线性回归分析结果提示高血压、吸烟和血浆同型半胱氨酸水平为冠心病患者冠状动脉病变SYNTAX评分的主要影响因素(P=0.001,0.009,0.014)。结论冠心病患者冠状动脉病变SYNTAX评分的主要影响因素有血浆同型半胱氨酸水平、血压、吸烟,其中,同型半胱氨酸水平越高,血压升高程度越明显,患者出现冠状动脉病变的风险越大。
目的:探討冠狀動脈粥樣硬化性心髒病(冠心病)患者冠狀動脈病變SYNTAX評分與冠心病易患因素的相關性。方法選取2011年4月至2013年4月駐馬店市第一人民醫院收治的117例冠心病患者為研究對象,依據患者SYNTAX評分分為低危組(31例)、中危組(37例)和高危組(49例)。採用Spearman秩相關分析和多元逐步迴歸分析探討冠狀動脈病變SYNTAX評分與冠心病易患因素的相關性。結果高危組患者吸煙率、糖尿病率、高血壓率、三酰甘油、同型半胱氨痠水平均顯著高于中危組[69.4%(34/49)比56.8%(21/37),48.9%(24/49)比35.1%(13/37),46.9%(23/49)比32.4%(12/37),(2.0±1.0) mmol/L比(1.8±0.9) mmol/L,(37±9)μmol/L比(24±8)μmol/L]、低危組[48.4%(15/31),22.6%(7/31),12.9%(4/31),(1.8±0.9) mmol/L,(16±7)μmol/L],差異有統計學意義(P<0.05),且中危組患者上述指標均高于低危組,差異有統計學意義( P<0.05)。多元線性迴歸分析結果提示高血壓、吸煙和血漿同型半胱氨痠水平為冠心病患者冠狀動脈病變SYNTAX評分的主要影響因素(P=0.001,0.009,0.014)。結論冠心病患者冠狀動脈病變SYNTAX評分的主要影響因素有血漿同型半胱氨痠水平、血壓、吸煙,其中,同型半胱氨痠水平越高,血壓升高程度越明顯,患者齣現冠狀動脈病變的風險越大。
목적:탐토관상동맥죽양경화성심장병(관심병)환자관상동맥병변SYNTAX평분여관심병역환인소적상관성。방법선취2011년4월지2013년4월주마점시제일인민의원수치적117례관심병환자위연구대상,의거환자SYNTAX평분분위저위조(31례)、중위조(37례)화고위조(49례)。채용Spearman질상관분석화다원축보회귀분석탐토관상동맥병변SYNTAX평분여관심병역환인소적상관성。결과고위조환자흡연솔、당뇨병솔、고혈압솔、삼선감유、동형반광안산수평균현저고우중위조[69.4%(34/49)비56.8%(21/37),48.9%(24/49)비35.1%(13/37),46.9%(23/49)비32.4%(12/37),(2.0±1.0) mmol/L비(1.8±0.9) mmol/L,(37±9)μmol/L비(24±8)μmol/L]、저위조[48.4%(15/31),22.6%(7/31),12.9%(4/31),(1.8±0.9) mmol/L,(16±7)μmol/L],차이유통계학의의(P<0.05),차중위조환자상술지표균고우저위조,차이유통계학의의( P<0.05)。다원선성회귀분석결과제시고혈압、흡연화혈장동형반광안산수평위관심병환자관상동맥병변SYNTAX평분적주요영향인소(P=0.001,0.009,0.014)。결론관심병환자관상동맥병변SYNTAX평분적주요영향인소유혈장동형반광안산수평、혈압、흡연,기중,동형반광안산수평월고,혈압승고정도월명현,환자출현관상동맥병변적풍험월대。
Objective To explore the correlation between coronary artery SYNTAX score and risk fac-tors of coronary heart disease.Methods A total of 117 patients with coronary heart disease in Zhumadian City First People′s Hospital from Apr.2011 to Apr.2013 were selected,according to SYNTAX score,the pa-tients were divided into the low risk group(31 cases), medium risk group(37 cases) and high risk group (49 cases).Spearman rank correlation analysis and multivariate stepwise regression were used to analyze the relationships between SYNTAX coronary artery score and risk factors for coronary heart disease.Results Smoking rate,diabetes mellitus, high blood pressure, triglyceride and homocysteine of the high risk group were significantly higher than the medium risk group[69.4%(34/49)vs 56.8%(21/37),48.9%(24/49) vs 35.1%(13/37),46.9%(23/49) vs 32.4%(12/37),(2.0 ±1.0) mmol/L vs (1.8 ±0.9) mmol/L, (37 ±9) μmol/L vs (24 ±8) μmol/L] and the low risk group[48.4%(15/31),22.6%(7/31),12.9%(4/31),(1.8 ±0.9) mmol/L,(16 ±7) μmol/L](P<0.05).Smoking rate,diabetes mellitus,high blood pressure, triglyceride and homocysteine of the medium risk group were significantly higher than the low risk group(P<0.05).Multiple stepwise regression analysis results suggested that hypertension,smoking and homocysteine were the main influencing factors of SYNTAX score of coronary artery lesion ( P =0.001, 0.009,0.014).Conclusion Plasma homocysteine,hypertension,smoking are main influencing factors of SYNTAX scores of coronary heart disease,the higher the level of homocysteine and blood pressure,the higher the risk of occurrence of coronary artery lesion.