CAJ | 학술논문

目的：探究哮喘患儿相关危险因素。方法对2013年3月至2014年3月西安市儿童医院收治的100例哮喘患儿（哮喘组）进行调查，并纳入同期100例健康体检儿童作为健康对照组，对发生儿童哮喘的危险因素进行分析。结果 Logistic多因素分析结果显示，家族哮喘史（ OR＝2.010，95％CI 1.100～3.673）、患儿／家族过敏史（OR ＝2.131，95％CI 1.192～3.810）、呼吸道感染（≥6次／年）（OR＝1.811，95％CI 1.252～2.620）、天气变化（OR＝2.301，95％CI 1.092～4.849）、毛绒／泡沫玩具（OR＝1.782，95％CI 1.202～2.642）以及母乳喂养比例少（OR＝2.111，95％CI 1.222～3.647）等均是影响儿童哮喘发生的危险因素（P＜0.05或 P ＜0.01）。结论导致哮喘患儿发病的相关危险因素存在多样性，遗传因素、不良环境因素及母乳喂养比例少均可增加儿童哮喘发病的风险，应引起临床重视。
목적：탐구효천환인상관위험인소。방법대2013년3월지2014년3월서안시인동의원수치적100례효천환인（효천조）진행조사，병납입동기100례건강체검인동작위건강대조조，대발생인동효천적위험인소진행분석。결과 Logistic다인소분석결과현시，가족효천사（ OR＝2.010，95％CI 1.100～3.673）、환인／가족과민사（OR ＝2.131，95％CI 1.192～3.810）、호흡도감염（≥6차／년）（OR＝1.811，95％CI 1.252～2.620）、천기변화（OR＝2.301，95％CI 1.092～4.849）、모융／포말완구（OR＝1.782，95％CI 1.202～2.642）이급모유위양비례소（OR＝2.111，95％CI 1.222～3.647）등균시영향인동효천발생적위험인소（P＜0.05혹 P ＜0.01）。결론도치효천환인발병적상관위험인소존재다양성，유전인소、불량배경인소급모유위양비례소균가증가인동효천발병적풍험，응인기림상중시。
Objective To explore related risk factors in children with asthma .Methods From Mar. 2013 to Mar.2014,100 children with asthma(asthma group) Xi′an Children′s Hospital were investigated, and another 100 healthy check-up children were included as healthy controls,to analyze childhood asthma risk factors.Results Logistic multi-factors analysis results showed that the family history of asthma ( OR=2.010,95% CI 1.100-3.673),children/family history of allergies(OR=2.131,95% CI 1.192-3.810), respiratory infections(≥6 times per year) OR higher(OR=1.811,95%CI 1.252-2.620),weather changes (OR=2.301,95% CI 1.092-4.849),plush/foam toys(OR =1.782,95% CI 1.202-2.642) and less breastfeeding rate(OR=2.111,95% CI 1.222-3.647), were independent risk factors for childhood asthma onset(P<0.05 or P<0.01).Conclusion The risk factors of asthma in children are diversified,such as genetic factors,environmental factors and little breastfeeding may all increase the risk of childhood asthma onset, to which due attention should be paid.