医学综述
醫學綜述
의학종술
Medical Recapitulate
2015年
18期
3454-3456
,共3页
宫颈上皮内瘤样病变%环形电切术%人乳头瘤病毒%持续感染%临床效果
宮頸上皮內瘤樣病變%環形電切術%人乳頭瘤病毒%持續感染%臨床效果
궁경상피내류양병변%배형전절술%인유두류병독%지속감염%림상효과
Cervical intraepithelial neoplasia%Loop electrosurgical excision procedure%Human papillo-mavirus%Persistent infection%Clinical effect
目的：探讨环形电切术治疗宫颈上皮内瘤样病变（ CIN）后人乳头瘤病毒（ HPV）持续感染临床效果。方法选取2011年2月至2013年2月大连市第三人民医院妇科收治的70例 CIN 后HPV持续感染患者为研究对象，采用随机数字表法分成两组，每组35例，对照组予以冷刀宫颈锥切术治疗，观察组用环形电切术治疗，观察两组治疗后临床效果。结果对照组手术残留率、治愈率、感染持续率和复发率分别为14.3％、68.5％、11.4％、14.3％；观察组手术残留率、治愈率、感染持续率和复发率分别为11.4％、80.0％、8.6％、11.4％，两组比较差异无统计学意义（ P ＞0.05）；而在术中出血量、手术时间、切口愈合时间、术后出血量、住院时间、HPV转阴时间和并发症发生率的比较，差异有统计学意义（ P＜0.05）。结论环形电切术不仅能切除高级CIN，且能清除高危型HPV持续感染，临床效果显著。
目的：探討環形電切術治療宮頸上皮內瘤樣病變（ CIN）後人乳頭瘤病毒（ HPV）持續感染臨床效果。方法選取2011年2月至2013年2月大連市第三人民醫院婦科收治的70例 CIN 後HPV持續感染患者為研究對象，採用隨機數字錶法分成兩組，每組35例，對照組予以冷刀宮頸錐切術治療，觀察組用環形電切術治療，觀察兩組治療後臨床效果。結果對照組手術殘留率、治愈率、感染持續率和複髮率分彆為14.3％、68.5％、11.4％、14.3％；觀察組手術殘留率、治愈率、感染持續率和複髮率分彆為11.4％、80.0％、8.6％、11.4％，兩組比較差異無統計學意義（ P ＞0.05）；而在術中齣血量、手術時間、切口愈閤時間、術後齣血量、住院時間、HPV轉陰時間和併髮癥髮生率的比較，差異有統計學意義（ P＜0.05）。結論環形電切術不僅能切除高級CIN，且能清除高危型HPV持續感染，臨床效果顯著。
목적：탐토배형전절술치료궁경상피내류양병변（ CIN）후인유두류병독（ HPV）지속감염림상효과。방법선취2011년2월지2013년2월대련시제삼인민의원부과수치적70례 CIN 후HPV지속감염환자위연구대상，채용수궤수자표법분성량조，매조35례，대조조여이냉도궁경추절술치료，관찰조용배형전절술치료，관찰량조치료후림상효과。결과대조조수술잔류솔、치유솔、감염지속솔화복발솔분별위14.3％、68.5％、11.4％、14.3％；관찰조수술잔류솔、치유솔、감염지속솔화복발솔분별위11.4％、80.0％、8.6％、11.4％，량조비교차이무통계학의의（ P ＞0.05）；이재술중출혈량、수술시간、절구유합시간、술후출혈량、주원시간、HPV전음시간화병발증발생솔적비교，차이유통계학의의（ P＜0.05）。결론배형전절술불부능절제고급CIN，차능청제고위형HPV지속감염，림상효과현저。
Objective To investigate the clinical effect of loop electrosurgical excision procedure trea-ting persistent human papilloma virus ( HPV ) infection after cervical intraepithelial neoplasia ( CIN ) treat-ment.Methods From Feb.2011 to Feb.2013,in Dalian Third People′s Hospital,70 cases of persistent CIN HPV infection were included in the study,and divided into two groups according to random number-table method,35 cases in each group:the control group received cold-knife conization treatment, the observation group received loop electrosurgical excision procedure,and the clinical effect of the two groups was observed after treatment.Results The postoperative residual rate, the cure rate, relapse rate and sustained infection rate of the control group were 14.3%, 68.5%, 11.4%, 14.3%;of the observation group were 11.4%, 80.0%, 8.6%, 11.4% respectively,no significant differences between the two groups(P>0.05);while the blood loss,operative time, wound healing time,postoperative blood loss,hospital stay,HPV turning nega-tive time and complication incidence of the two groups had statistically significant difference(P <0.05). Conclusion Loop electrosurgical excision procedure not only can cut advanced CIN,but also can remove persistent high-risk HPV infection,with significant clinical effect.
