刑事技术
刑事技術
형사기술
Forensic Science and Technology
2015年
5期
424-425
,共2页
法医遗传学%遗传多态性%Y 染色体短串联重复序列%汉族
法醫遺傳學%遺傳多態性%Y 染色體短串聯重複序列%漢族
법의유전학%유전다태성%Y 염색체단천련중복서렬%한족
forensic genetics%genetic polymorphism%Y chromosomal short tandem repeat%Han population
应用 Y-filer 荧光标记复合扩增试剂盒对济宁地区5585名汉族男性个体血样 DNA 进行分型,统计分析16个 Y-STR 基因座的遗传学参数，DYS391、DYS389I、DYS439、DYS389II、DYS438、DYS456、DYS458、DYS437、DYS635、DYS448、Y_GATA_H4、DYS19、DYS393、DYS390、DYS392、DYS385a/b 基因座分别检出5~13种等位基因，DYS385a/b 基因座共检出99个单倍型。基因座频率分布在0.0002~0.7560之间，基因多样性（GD）分布在0.3972~0.9634之间。16个 Y-STR 基因座在济宁汉族群体具有丰富的遗传多态性，可用于群体遗传学及法医学研究。
應用 Y-filer 熒光標記複閤擴增試劑盒對濟寧地區5585名漢族男性箇體血樣 DNA 進行分型,統計分析16箇 Y-STR 基因座的遺傳學參數，DYS391、DYS389I、DYS439、DYS389II、DYS438、DYS456、DYS458、DYS437、DYS635、DYS448、Y_GATA_H4、DYS19、DYS393、DYS390、DYS392、DYS385a/b 基因座分彆檢齣5~13種等位基因，DYS385a/b 基因座共檢齣99箇單倍型。基因座頻率分佈在0.0002~0.7560之間，基因多樣性（GD）分佈在0.3972~0.9634之間。16箇 Y-STR 基因座在濟寧漢族群體具有豐富的遺傳多態性，可用于群體遺傳學及法醫學研究。
응용 Y-filer 형광표기복합확증시제합대제저지구5585명한족남성개체혈양 DNA 진행분형,통계분석16개 Y-STR 기인좌적유전학삼수，DYS391、DYS389I、DYS439、DYS389II、DYS438、DYS456、DYS458、DYS437、DYS635、DYS448、Y_GATA_H4、DYS19、DYS393、DYS390、DYS392、DYS385a/b 기인좌분별검출5~13충등위기인，DYS385a/b 기인좌공검출99개단배형。기인좌빈솔분포재0.0002~0.7560지간，기인다양성（GD）분포재0.3972~0.9634지간。16개 Y-STR 기인좌재제저한족군체구유봉부적유전다태성，가용우군체유전학급법의학연구。
Objective To investigate the genetic polymorphism of 16 Y-chromosomal short tandem repeats (Y-STR) loci in Han population in Jining area and to evaluate its forensic significance through comparison with the frequencies distribution of some loci in settlement-different people. Methods Blood samples were collected from 5585 male individuals of Han-population in Jining area. 16 Y-STR loci were amplified with Y-filer PCR Amplification Kit. Genotypes and frequencies of alleles were obtained by ID-X GeneMapper analysis software. The frequency distribution on some loci was statistically compared with same or different people in various settlements. Results Of 5585 male individuals, 5~13 kinds of alleles were found among the 16 Y-STR loci of DYS391, DYS389I, DYS439, DYS389II, DYS438, DYS456, DYS458, DYS437, DYS635, DYS448, Y_GATA_H4, DYS19, DYS393, DYS390, DYS392, DYS385a/b and with the last one DYS385a/b having 99 haplotypes. Frequencies of the above 16 Y-STR loci ranged from 0.0002 to 0.640, and the gene diversity 0.3972 to 0.9634. Conclusions The 16 Y-STR loci are of highly genetic polymorphism in Han population in Jining area, suitable for genetics and forensic research.
