CAJ | 학술논문

目的：探讨血清β人绒毛膜促性腺激素(β-HCG)与孕早期血脂对预测妊娠高血压疾病的价值。方法选取2011年1月至2014年1月入住我院的妊娠高血压产妇150例，设为妊娠高血压组，另选取同期入住我院的正常健康产妇150例为正常对照组。比较两组孕妇一般性资料、孕早期(37~60天)血脂水平以及妊娠中期血清β-HCG水平，分析孕妇并发妊娠高血压的危险因素。结果妊高组患者的β-HCG、甘油三酯、胆固醇、高密度脂蛋白、低密度脂蛋白水平均明显高于正常组，差异具有统计学意义(P＜0.05)。 Logistic回归分析显示，甘油三酯(OR =2.561)、高密度脂蛋白(OR =2.023)、β-HCG (OR =1.347)和低密度脂蛋白(OR =1.248)均是导致妊娠高血压的危险因素。结论血清β人绒毛膜促性腺激素与孕早期血脂均是导致妊娠高血压的危险因素，可以作为妊高症诊断的临床参考。
목적：탐토혈청β인융모막촉성선격소(β-HCG)여잉조기혈지대예측임신고혈압질병적개치。방법선취2011년1월지2014년1월입주아원적임신고혈압산부150례，설위임신고혈압조，령선취동기입주아원적정상건강산부150례위정상대조조。비교량조잉부일반성자료、잉조기(37~60천)혈지수평이급임신중기혈청β-HCG수평，분석잉부병발임신고혈압적위험인소。결과임고조환자적β-HCG、감유삼지、담고순、고밀도지단백、저밀도지단백수평균명현고우정상조，차이구유통계학의의(P＜0.05)。 Logistic회귀분석현시，감유삼지(OR =2.561)、고밀도지단백(OR =2.023)、β-HCG (OR =1.347)화저밀도지단백(OR =1.248)균시도치임신고혈압적위험인소。결론혈청β인융모막촉성선격소여잉조기혈지균시도치임신고혈압적위험인소，가이작위임고증진단적림상삼고。
Objective To explore the value of serumβhuman chorionic gonadotropin (β-HCG) and blood lipid in early pregnancy in predicting pregnancy-induced hypertension disease. Methods 150 cases of pregnant women with pregnancy-induced hypertension disease admitted to our hospital from January 2011 to January 2014 were selected as gestational hypertension group, 150 cases of healthy pregnant women admitted to our hospital in same period were set as normal group. The general information, levels of blood lipid in early pregnancy (37 ~ 60 d) and serum β-HCG level in second trimester of pregnancy were compared between two groups, the risk factors of pregnancy-induced hypertension was analyzed. Results The levels ofβ-HCG, triglyceride, cholesterol, high-density lipoprotein, low density lipoprotein in gestational hypertension group were significantly higher than those in control group, with statistical difference (P<0.05). The analysis of Logistic regression showed that triglyceride (OR =2.561), high-density lipoprotein (OR =2.023),β-HCG (OR =1.347) and low density lipoprotein (OR=1.248) were the risk factors for pregnancy-induced hypertension. Conclusions The serumβ-HCG and blood lipid in early pregnancy are the risk factors for pregnancy-induced hypertension, which can serve as the clinical reference for the diagnosis of pregnancy-induced hypertension.