中国实用医刊
中國實用醫刊
중국실용의간
Chinese Journal of Practical Medicine
2015年
21期
11-12
,共2页
肿瘤%反复输血%交叉配血%影响
腫瘤%反複輸血%交扠配血%影響
종류%반복수혈%교차배혈%영향
Tumor%Repeated blood transfusions%Cross matching%Influence
目的：研究肿瘤患者多次反复输血对交叉配血结果的影响。方法选取安阳市肿瘤医院152例肿瘤患者和127例非肿瘤患者进行病例样本研究，分别设为肿瘤组与非肿瘤组，根据实际输血次数将肿瘤组患者分为2～5次输血组与6次以上多次输血组，配血结果通过微柱凝胶法及凝聚胺法进行分析。比较肿瘤组与非肿瘤组、2～5次输血及≥6次输血的交叉配血结果。结果肿瘤组凝聚胺法、微柱凝胶法测定相合率分别为90．13％、84．87％，不相合率分别为9．87％、18．11％，与非肿瘤组相合率（97．64％、94．85％）及不相合率（2．36％、3．15％）比较差异有统计学意义（ P＜0．05）；输血2～5次患者凝聚胺法和微柱凝胶法检测相合率为94．12％、88．2％，不相合率为5．88％、11．76％，与≥6次患者相合率（89．55％、82．09％）、不相合率（10．45％、17．91％）比较差异有统计学意义（P＜0．05）；两种交叉配血检测方式比较，凝聚胺法高于微柱凝胶法，差异均有统计学意义（P＜0．05）。结论肿瘤患者较非肿瘤患者交叉配血符合率较低，而输血次数和输血量与配血符合率呈负相关，对此应加强高危患者的临床防范，并将微柱凝胶法设为优选方案。
目的：研究腫瘤患者多次反複輸血對交扠配血結果的影響。方法選取安暘市腫瘤醫院152例腫瘤患者和127例非腫瘤患者進行病例樣本研究，分彆設為腫瘤組與非腫瘤組，根據實際輸血次數將腫瘤組患者分為2～5次輸血組與6次以上多次輸血組，配血結果通過微柱凝膠法及凝聚胺法進行分析。比較腫瘤組與非腫瘤組、2～5次輸血及≥6次輸血的交扠配血結果。結果腫瘤組凝聚胺法、微柱凝膠法測定相閤率分彆為90．13％、84．87％，不相閤率分彆為9．87％、18．11％，與非腫瘤組相閤率（97．64％、94．85％）及不相閤率（2．36％、3．15％）比較差異有統計學意義（ P＜0．05）；輸血2～5次患者凝聚胺法和微柱凝膠法檢測相閤率為94．12％、88．2％，不相閤率為5．88％、11．76％，與≥6次患者相閤率（89．55％、82．09％）、不相閤率（10．45％、17．91％）比較差異有統計學意義（P＜0．05）；兩種交扠配血檢測方式比較，凝聚胺法高于微柱凝膠法，差異均有統計學意義（P＜0．05）。結論腫瘤患者較非腫瘤患者交扠配血符閤率較低，而輸血次數和輸血量與配血符閤率呈負相關，對此應加彊高危患者的臨床防範，併將微柱凝膠法設為優選方案。
목적：연구종류환자다차반복수혈대교차배혈결과적영향。방법선취안양시종류의원152례종류환자화127례비종류환자진행병례양본연구，분별설위종류조여비종류조，근거실제수혈차수장종류조환자분위2～5차수혈조여6차이상다차수혈조，배혈결과통과미주응효법급응취알법진행분석。비교종류조여비종류조、2～5차수혈급≥6차수혈적교차배혈결과。결과종류조응취알법、미주응효법측정상합솔분별위90．13％、84．87％，불상합솔분별위9．87％、18．11％，여비종류조상합솔（97．64％、94．85％）급불상합솔（2．36％、3．15％）비교차이유통계학의의（ P＜0．05）；수혈2～5차환자응취알법화미주응효법검측상합솔위94．12％、88．2％，불상합솔위5．88％、11．76％，여≥6차환자상합솔（89．55％、82．09％）、불상합솔（10．45％、17．91％）비교차이유통계학의의（P＜0．05）；량충교차배혈검측방식비교，응취알법고우미주응효법，차이균유통계학의의（P＜0．05）。결론종류환자교비종류환자교차배혈부합솔교저，이수혈차수화수혈량여배혈부합솔정부상관，대차응가강고위환자적림상방범，병장미주응효법설위우선방안。
Objective To analyze the influence of repeated blood transfusions on the results of cross matching of blood.Methods One hundred and fifty-two tumor patients and 127 no-cancer patients were divided into two groups according to the presence of tumor.Tumor patients were divided into two groups according to the numbers of blood transfusion, a group of blood transfusion 2-5 times and another group of blood transfusion more than 6 times.Cross matching results performed by microcolumn gel test ( MGT) and moditying polybrene test( MPT) were compared.Results The MGT and MPT consistency rate of tumor patients was 90.13%and 84.87%, which was significantly lower than that of no-cancer pa-tients(P<0.05).The MGT and MPT consistency rate of tumor patients with 2-5 times blood transfu-sion was 94.12%and 88.2%, there was significant difference in the consistency rate between the result of two crossmatching methods in the tumor group(P<0.05).There was significant difference between the results of two cross matching methods ( P<0.05 ) .Conclusions The tumor patients have lower cross matching consistency rate than the no-cancer patients.The cross matching consistency rate of the tumor patients reduce with the increase of the number of blood transfusions.The MGT is more sensitive than MPT in cross matching of blood.
