CAJ | 학술논문

目的：探讨采用FLAG方案对难治复发白血病进行治疗的临床效果。方法随机选取商丘市第一人民医院2011年9月至2014年3月收治的难治复发白血病患者90例，按照治疗方案的不同将其随机分为实验组和对照组，其中对照组患者采用MEA方案进行治疗，实验组患者采用FLAG方案进行治疗，对比两组患者的临床治疗效果及其不良反应发生情况。结果实验组患者的完全缓解率、总有效率明显高于对照组（P＜0．05），两组患者不良反应发生情况比较差异未见统计学意义（ P＞0．05）。结论采用FLAG方案对难治复发白血病进行治疗，疗效显著，安全可靠，建议在临床上进一步推广。
목적：탐토채용FLAG방안대난치복발백혈병진행치료적림상효과。방법수궤선취상구시제일인민의원2011년9월지2014년3월수치적난치복발백혈병환자90례，안조치료방안적불동장기수궤분위실험조화대조조，기중대조조환자채용MEA방안진행치료，실험조환자채용FLAG방안진행치료，대비량조환자적림상치료효과급기불량반응발생정황。결과실험조환자적완전완해솔、총유효솔명현고우대조조（P＜0．05），량조환자불량반응발생정황비교차이미견통계학의의（ P＞0．05）。결론채용FLAG방안대난치복발백혈병진행치료，료효현저，안전가고，건의재림상상진일보추엄。
Objective To investigate the clinical efficacy of FLAG program on the refractory and relapsed leukemia.Methods Randomly selected 90 patients with refractory leukemia relapse in the first people’ s hospital of Shangqiu from September 2011 to 2014 and randomly divided them into experiment group and control group according to different treatment regimens.The control group was treated with MEA treatment program, and the experiment group was treated with FLAG regimen for treatment.The clinical effects and adverse reactions of the two groups were observed and compared.Results The com-plete remission rate and total effective rate in the experiment group were significantly higher than those of control group( P<0.05) , and the difference of adverse reactions between the two groups was not signifi-cant ( P>0.05) .Conclusions FLAG scheme is effective, safe and reliable in treatment of refractory and relapsed leukemia, so it is recommended to further promoted in clinical practice.