中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2015年
38期
3110-3114
,共5页
徐明月%史宪杰%万涛%王宏光%何蕾%陈明易%梁雨荣%董家鸿
徐明月%史憲傑%萬濤%王宏光%何蕾%陳明易%樑雨榮%董傢鴻
서명월%사헌걸%만도%왕굉광%하뢰%진명역%량우영%동가홍
囊腺癌%囊腺瘤%胆管,肝内%预后%男性
囊腺癌%囊腺瘤%膽管,肝內%預後%男性
낭선암%낭선류%담관,간내%예후%남성
Cystadenocarcinoma%Cystadenoma%Bile ducts,Intrahepatic%Prognosis%Male
目的 比较肝内胆管囊性肿瘤(IBCT)男性与女性患者的临床特征及预后差异.方法 回顾性分析2003年1月至2014年4月解放军总医院经术后病理证实为IBCT的56例患者的临床资料,分析男性与女性患者的临床特征、实验室检查、影像学特征、治疗方式及预后.结果 男性患者平均年龄为(54.9±10.1)岁,明显大于女性的(46.2±12.9)岁,差异有统计学意义(P=0.041).除男性患者更易出现肿瘤内乳头状结构外(10/11与15/45,P=0.001),二者在影像学特征方面差异无统计学意义.男性患者中肝内胆管囊腺癌(IBC)的比例明显高于女性(8/11与16/45,P=0.041),其预后也差于女性(P=0.014),男性患者的1、3、5年生存率为90.9％,45.5％,30.3％,女性患者的1、3、5年生存率为94.8％,82.7％,78.6％.结论 男性肝内胆管囊性肿瘤发病率较低,且多为IBC,即使完整切除后预后仍较差,术后仍需密切随访.
目的 比較肝內膽管囊性腫瘤(IBCT)男性與女性患者的臨床特徵及預後差異.方法 迴顧性分析2003年1月至2014年4月解放軍總醫院經術後病理證實為IBCT的56例患者的臨床資料,分析男性與女性患者的臨床特徵、實驗室檢查、影像學特徵、治療方式及預後.結果 男性患者平均年齡為(54.9±10.1)歲,明顯大于女性的(46.2±12.9)歲,差異有統計學意義(P=0.041).除男性患者更易齣現腫瘤內乳頭狀結構外(10/11與15/45,P=0.001),二者在影像學特徵方麵差異無統計學意義.男性患者中肝內膽管囊腺癌(IBC)的比例明顯高于女性(8/11與16/45,P=0.041),其預後也差于女性(P=0.014),男性患者的1、3、5年生存率為90.9％,45.5％,30.3％,女性患者的1、3、5年生存率為94.8％,82.7％,78.6％.結論 男性肝內膽管囊性腫瘤髮病率較低,且多為IBC,即使完整切除後預後仍較差,術後仍需密切隨訪.
목적 비교간내담관낭성종류(IBCT)남성여녀성환자적림상특정급예후차이.방법 회고성분석2003년1월지2014년4월해방군총의원경술후병리증실위IBCT적56례환자적림상자료,분석남성여녀성환자적림상특정、실험실검사、영상학특정、치료방식급예후.결과 남성환자평균년령위(54.9±10.1)세,명현대우녀성적(46.2±12.9)세,차이유통계학의의(P=0.041).제남성환자경역출현종류내유두상결구외(10/11여15/45,P=0.001),이자재영상학특정방면차이무통계학의의.남성환자중간내담관낭선암(IBC)적비례명현고우녀성(8/11여16/45,P=0.041),기예후야차우녀성(P=0.014),남성환자적1、3、5년생존솔위90.9％,45.5％,30.3％,녀성환자적1、3、5년생존솔위94.8％,82.7％,78.6％.결론 남성간내담관낭성종류발병솔교저,차다위IBC,즉사완정절제후예후잉교차,술후잉수밀절수방.
Objective To describe the clinicopathological characteristics and prognosis of intrahepatic biliary cystic tumor (IBCT) and compare the difference betwwen male and female patients.Methods 11 male and 45 female patients with histological confirmed IBCT from January 2003 to April 2014 were envolved.clinical characteristics,laboratory examination,radiological features,treatment method and prognosis were analyzed.Results The mean age of male patients with IBCT was significantly older than that of female patients (54.9 ± 10.1 years vs 46.2 ± 12.9 years,P =0.041).There were no significant differences in radiological features between male and female patients except for mural nodules (10/11 vs 15/45,P =0.001).Intrahepatic biliary cystadenocarcinoma (IBC) was more common in male patients than female patients (8/11 vs 16/45,P =0.041).Male patients had worse prognosis than female patients (P =0.014).1-year,3-year,and 5-year survival of male patients was 90.9％,45.5％,30.3％,respectively.However,1-year,3-year,and 5-year survival of female patients was 94.8％,82.7％,78.6％.Conclusions Male patients had low incidence of IBCT,and were more common for IBC.Even with complete resection,the long-term survival was still poor,close follow-up were recommended especially for male patients.
