CAJ | 학술논문

目的：：了解开平城区人群高尿酸血症的患病情况。方法：对2014年1月－12月在本院体检中心进行健康体检的10101人的尿酸数据进行统计,收集所有入组人员的性别、体重、年龄情况,采集患者禁食12 h后的静脉血,测定尿酸、肌酐值。结果：总人群尿酸平均值为(367.33±93.65)μmol/L,男性尿酸平均值为(402.53±83.23)μmol/L,女性尿酸平均值为(298.77±70.97)μmol/L。结论：女性的平均尿酸值明显低于男性(P<0.05)；同年龄组相比较,女性高尿酸血症的患病率也明显低于男性(P<0.05)；且女性的高尿酸血症患病率随着年龄增加及肾脏滤过率的降低而逐渐增加( P<0.05)；男性的患病率在不同年龄组间差异不明显且在30~49岁年龄段稍高。
목적：：료해개평성구인군고뇨산혈증적환병정황。방법：대2014년1월－12월재본원체검중심진행건강체검적10101인적뇨산수거진행통계,수집소유입조인원적성별、체중、년령정황,채집환자금식12 h후적정맥혈,측정뇨산、기항치。결과：총인군뇨산평균치위(367.33±93.65)μmol/L,남성뇨산평균치위(402.53±83.23)μmol/L,녀성뇨산평균치위(298.77±70.97)μmol/L。결론：녀성적평균뇨산치명현저우남성(P<0.05)；동년령조상비교,녀성고뇨산혈증적환병솔야명현저우남성(P<0.05)；차녀성적고뇨산혈증환병솔수착년령증가급신장려과솔적강저이축점증가( P<0.05)；남성적환병솔재불동년령조간차이불명현차재30~49세년령단초고。
Objective:To determine the prevalence of hyperuricemia of urban residents in Kaiping city. Methods:10 101 residents who had regular health checkup in our hospital from January to December2014 were selected. The information of all the subjects, including uric acid levels, gender, weight and age was collected and analyzed. Venous blood was collected after 12 hours fasting for biochemical examination. Results: The average serum uric acid level of the total population was (367.33±93.65) μmol/L, males (402.53±83.23) μmol/L, females (298.77±70.97) μmol/L. Conclusion: The average serum uric acid level in females was significantly lower than that in males. In the same age group, the prevalence of hyperuricemia among females was significantly lower than that among males(P<0.05).The prevalence of hyperuricemia in females increased with age, but was negatively related with estimated glomerular filtration rate ( eGFR ) ( P<0. 05 ) . There were no significant differences of prevalence of hyperuricemia in males among different age groups; however, the prevalence was slightly higher in those aged 30-49.