中外医疗
中外醫療
중외의료
China Foreign Medical Treatment
2015年
28期
153-155
,共3页
盐酸吗啡缓释片%口服给药%直肠给药%癌痛%不良反应
鹽痠嗎啡緩釋片%口服給藥%直腸給藥%癌痛%不良反應
염산마배완석편%구복급약%직장급약%암통%불량반응
Morphine hydrochloride%Oral administration%Rectal administration%Cancer pain%Adverse reaction
目的 分析和探讨盐酸吗啡缓释片口服与直肠给药控制癌痛疗效及不良反应. 方法 整群选取该院2013年2月—2014年2月收治的64例癌痛患者,分为口服给药组(n=32)和直肠给药组(n=32),口服给药组为盐酸吗啡缓释片口服,直肠给药组是将盐酸吗啡缓释片通过直肠给药,对两组患者临床治疗效果及不良反应作比较分析. 结果 治疗后直肠给药组患者生活满意度显著高于口服给药组(P<0.05);直肠给药组患者消化道不良反应发生率较对照组更低(P<0.05),其它不良反应发生率低于对照组,但差异无统计学意义(P>0.05). 结论 盐酸吗啡缓释片口服给药和直肠给药均能实现不错的临床效果,但直肠给药不良反应相对较少,是一种安全、简单、疗效显著的给药方式,值得临床推广应用.
目的 分析和探討鹽痠嗎啡緩釋片口服與直腸給藥控製癌痛療效及不良反應. 方法 整群選取該院2013年2月—2014年2月收治的64例癌痛患者,分為口服給藥組(n=32)和直腸給藥組(n=32),口服給藥組為鹽痠嗎啡緩釋片口服,直腸給藥組是將鹽痠嗎啡緩釋片通過直腸給藥,對兩組患者臨床治療效果及不良反應作比較分析. 結果 治療後直腸給藥組患者生活滿意度顯著高于口服給藥組(P<0.05);直腸給藥組患者消化道不良反應髮生率較對照組更低(P<0.05),其它不良反應髮生率低于對照組,但差異無統計學意義(P>0.05). 結論 鹽痠嗎啡緩釋片口服給藥和直腸給藥均能實現不錯的臨床效果,但直腸給藥不良反應相對較少,是一種安全、簡單、療效顯著的給藥方式,值得臨床推廣應用.
목적 분석화탐토염산마배완석편구복여직장급약공제암통료효급불량반응. 방법 정군선취해원2013년2월—2014년2월수치적64례암통환자,분위구복급약조(n=32)화직장급약조(n=32),구복급약조위염산마배완석편구복,직장급약조시장염산마배완석편통과직장급약,대량조환자림상치료효과급불량반응작비교분석. 결과 치료후직장급약조환자생활만의도현저고우구복급약조(P<0.05);직장급약조환자소화도불량반응발생솔교대조조경저(P<0.05),기타불량반응발생솔저우대조조,단차이무통계학의의(P>0.05). 결론 염산마배완석편구복급약화직장급약균능실현불착적림상효과,단직장급약불량반응상대교소,시일충안전、간단、료효현저적급약방식,치득림상추엄응용.
Objective To analyze and evaluate the hydrochloride oral and rectal morphine administration control and adverse reac-tion of cancer pain treatment. Methods In our hospital in 2013 February February 2014 from 64 cases of cancer patients was giv-en to treatment group (n=32) and rectum give medicine group (n=32), oral administration group for morphine hydrochloride sus-tained-release tablets, rectum give medicine group is the morphine hydrochloride sustained-release tablets by rectal administra-tion, of two groups of patients and the clinical efficacy and adverse reactions were compared. Results After treatment of rectum to the satisfaction of life of patients in treatment group was significantly higher than that of oral administration group ( P<0.05);rectal drug groups of patients with gastrointestinal adverse reaction incidence were lower than the control group (P<0.05). Other adverse reactions occurred were lower than that of the control group, but the difference was not statistically significant (P>0.05). Conclu-sion Morphine hydrochloride sustained release tablets by oral administration and rectal administration can achieve good clinical results, but rectal to adverse drug reaction is relatively less is a safe, simple, efficacy significantly to medicine,is worthy of clinical application.
