中外医疗
中外醫療
중외의료
China Foreign Medical Treatment
2015年
28期
38-39
,共2页
血清降钙素原%新生儿肺炎%新生儿败血症%高胆红素血症
血清降鈣素原%新生兒肺炎%新生兒敗血癥%高膽紅素血癥
혈청강개소원%신생인폐염%신생인패혈증%고담홍소혈증
Serum procalcitonin%Neonatal pneumonia%Neonatal sepsis%Hyperbilirubinemia
目的 探讨血清降钙素原(PCT)在新生儿感染性疾病应用价值. 方法 将该院儿科2013年12月—2014年12月收治的288例住院新生儿分别归入重症感染组(64例)、一般感染组(132例)、非感染组(92例),采用电化学发光法检测患儿血清降钙素原(PCT)水平变化.结果 一般感染组132例,降钙素原阳性46例,阳性率34.85%,阴性86例;重症感染组64例,降钙素原阳性40例,阳性率62.5%,阴性24例;非感染组92例,降钙素原阳性9例,阳性率9.78%,阴性83例. 重症感染组PCT阳性率最高,一般感染组其次,非感染组阳性率最低,差异有统计学意义(P<0.05);所有患儿血清降钙素原值随病情的好转而降低,差异有统计学意义(P<0.05). 结论 ①通过检测288例患儿血清PCT水平可以明确患儿的感染情况,可有效鉴别细菌感染;②新生儿肺炎有多种病因,并非细菌感染一种,PCT检测可作为新生儿感染性肺炎的鉴别指标,为临床合理使用抗生素提供理论依据.
目的 探討血清降鈣素原(PCT)在新生兒感染性疾病應用價值. 方法 將該院兒科2013年12月—2014年12月收治的288例住院新生兒分彆歸入重癥感染組(64例)、一般感染組(132例)、非感染組(92例),採用電化學髮光法檢測患兒血清降鈣素原(PCT)水平變化.結果 一般感染組132例,降鈣素原暘性46例,暘性率34.85%,陰性86例;重癥感染組64例,降鈣素原暘性40例,暘性率62.5%,陰性24例;非感染組92例,降鈣素原暘性9例,暘性率9.78%,陰性83例. 重癥感染組PCT暘性率最高,一般感染組其次,非感染組暘性率最低,差異有統計學意義(P<0.05);所有患兒血清降鈣素原值隨病情的好轉而降低,差異有統計學意義(P<0.05). 結論 ①通過檢測288例患兒血清PCT水平可以明確患兒的感染情況,可有效鑒彆細菌感染;②新生兒肺炎有多種病因,併非細菌感染一種,PCT檢測可作為新生兒感染性肺炎的鑒彆指標,為臨床閤理使用抗生素提供理論依據.
목적 탐토혈청강개소원(PCT)재신생인감염성질병응용개치. 방법 장해원인과2013년12월—2014년12월수치적288례주원신생인분별귀입중증감염조(64례)、일반감염조(132례)、비감염조(92례),채용전화학발광법검측환인혈청강개소원(PCT)수평변화.결과 일반감염조132례,강개소원양성46례,양성솔34.85%,음성86례;중증감염조64례,강개소원양성40례,양성솔62.5%,음성24례;비감염조92례,강개소원양성9례,양성솔9.78%,음성83례. 중증감염조PCT양성솔최고,일반감염조기차,비감염조양성솔최저,차이유통계학의의(P<0.05);소유환인혈청강개소원치수병정적호전이강저,차이유통계학의의(P<0.05). 결론 ①통과검측288례환인혈청PCT수평가이명학환인적감염정황,가유효감별세균감염;②신생인폐염유다충병인,병비세균감염일충,PCT검측가작위신생인감염성폐염적감별지표,위림상합리사용항생소제공이론의거.
Objective To investigate the value of serum procalcitonin (PCT) applied to neonatal infectious diseases. Methods 288 neonates hospitalized in Department of Pediatrics of our hospital from December 2013 to December 2014 were divided into severe infection group (64 cases), general infection group (132 cases), non-infected group (92 cases). Electrochemical luminescence method was used to test the level of serum PCT in the neonates. Results Of the 132 cases in the general infection group, 46 cases had positive procalcitonin with the positive rate of 34.85%, 86 cases had negative procalcitonin. Of the 64 cases in the severe in-fection group, 40 cases had positive procalcitonin with the positive rate of 62.5%, 24 cases had negative procalcitonin. Of the 92 cases in the non-infected group, 9 cases had positive procalcitonin with the positive rate of 9.78%, 83 cases had negative procal-citonin. The severe infection group had the highest positive rate of PCT, followed by the general infection group, and the non-in-fected group had the lowest positive rate of PCT with statistically significant difference (P<0.05). The level of PCT in all the neonates decreased as the disease improved with statistically significant difference (P<0.05). Conclusion ①The infection of the neonates and bacterial infection can be effectively identified by testing the level of serum PCT in 288 neonates. ②Many reasons including bacterial infection can cause neonatal pneumonia. PCT testing can be used as the identification index of neonatal infec-tious pneumonia, which provides a theoretical basis for the clinical rational use of antibiotics.
