中外医疗
中外醫療
중외의료
China Foreign Medical Treatment
2015年
28期
32-33
,共2页
自体角膜缘干细胞移植%生物羊膜移植%翼状胬肉
自體角膜緣榦細胞移植%生物羊膜移植%翼狀胬肉
자체각막연간세포이식%생물양막이식%익상노육
Autologous corneal limbal stem cell transplantation%Biological amniotic membrane transplantation%Pterygium
目的 探究分析自体角膜缘干细胞移植与生物羊膜移植治疗翼状胬肉的临床效果. 方法 整群选取2013年7月—2014年12月该院收治的87例(98眼)翼状胬肉患者并随机分为自体角膜缘干细胞移植组(A组,n=44例)与生物羊膜移植组(B组,n=43例). 两组患者术后均随访1年,观察患者术后角膜上皮愈合时间、复发情况及视力恢复情况. 结果 A组患者术后角膜上皮愈合时间显著低于B组,差异有统计学意义(P<0.05);两组患者术后视力恢复情况无显著性差异(P>0.05);A组患者术后复发率为2.27%,B组患者术后复发率为13.95%,两组相比差异有统计学意义(χ2=4.010,P<0.05). 结论 自体角膜缘干细胞移植与生物羊膜移植治疗翼状胬肉均取得良好效果, 相比之下自体角膜缘干细胞移植术后角膜上皮愈合快、复发率低,治疗效果更为理想.
目的 探究分析自體角膜緣榦細胞移植與生物羊膜移植治療翼狀胬肉的臨床效果. 方法 整群選取2013年7月—2014年12月該院收治的87例(98眼)翼狀胬肉患者併隨機分為自體角膜緣榦細胞移植組(A組,n=44例)與生物羊膜移植組(B組,n=43例). 兩組患者術後均隨訪1年,觀察患者術後角膜上皮愈閤時間、複髮情況及視力恢複情況. 結果 A組患者術後角膜上皮愈閤時間顯著低于B組,差異有統計學意義(P<0.05);兩組患者術後視力恢複情況無顯著性差異(P>0.05);A組患者術後複髮率為2.27%,B組患者術後複髮率為13.95%,兩組相比差異有統計學意義(χ2=4.010,P<0.05). 結論 自體角膜緣榦細胞移植與生物羊膜移植治療翼狀胬肉均取得良好效果, 相比之下自體角膜緣榦細胞移植術後角膜上皮愈閤快、複髮率低,治療效果更為理想.
목적 탐구분석자체각막연간세포이식여생물양막이식치료익상노육적림상효과. 방법 정군선취2013년7월—2014년12월해원수치적87례(98안)익상노육환자병수궤분위자체각막연간세포이식조(A조,n=44례)여생물양막이식조(B조,n=43례). 량조환자술후균수방1년,관찰환자술후각막상피유합시간、복발정황급시력회복정황. 결과 A조환자술후각막상피유합시간현저저우B조,차이유통계학의의(P<0.05);량조환자술후시력회복정황무현저성차이(P>0.05);A조환자술후복발솔위2.27%,B조환자술후복발솔위13.95%,량조상비차이유통계학의의(χ2=4.010,P<0.05). 결론 자체각막연간세포이식여생물양막이식치료익상노육균취득량호효과, 상비지하자체각막연간세포이식술후각막상피유합쾌、복발솔저,치료효과경위이상.
Objective To explore and analyze the clinical effect of autologous corneal limbal stem cell transplantation and biologi-cal amniotic membrane transplantation on pterygium. Methods Eighty-seven cases (98 eyes) with pterygium admitted in our hospi-tal from July 2013 to December 2014 were selected and randomly divided into autologous corneal limbal stem cell transplantation group (group A, 44 cases) and biological amniotic membrane transplantation group (group B, 43 cases). Both groups were followed up for 1 year after surgery. The postoperative corneal epithelium healing time, the recurrence of pterygium and the recovery of vi-sual acuity of the two groups were observed. Results The postoperative corneal epithelial healing time of group A was much shorter than that of group B with statistically significant difference (P<0.05). No difference was found in the postoperative recovery of visu-al acuity between the two groups (P>0.05). The postoperative recurrence rate of pterygium was 2.27% in group A, and 13.95% in group B, the difference between the two groups was statistically significant (χ2=4.010, P<0.05). Conclusion Both autologous corneal limbal stem cell transplantation and biological amniotic membrane transplantation have good effect on pterygium, but pa-tients with autologous corneal limbal stem cell transplantation have quicker postoperative corneal epithelium healing and lower re-currence rate of pterygium with better treatment effect.
