CAJ | 학술논문

目的：：探讨COOK宫颈扩张球囊在足月妊娠促宫颈成熟引产中的临床效果及安全性。方法：回顾性分析2011年9月至2014年10月广州市花都区妇幼保健院收治的300例足月妊娠有引产指征孕妇的临床资料,根据促宫颈成熟方式的不同分为研究组( COOK宫颈扩张球囊,173例)和对照组(地诺前列酮栓,127例),比较两组促宫颈成熟情况、引产结局、新生儿结局及引产过程差异。结果：置入或用药后两组Bishop评分均较治疗前提高(P<0.05),但两组之间差异无统计学意义(P>0.05)。研究组缩宫素使用率、引产成功率、阴道分娩率高于对照组,产后出血量、剖宫产率低于对照组( P<0.05)；两组第一产程时间、宫颈裂伤发生率、阴道血肿率、新生儿体质量、新生儿窒息率、新生儿窘迫率、新生儿第1分钟Apgar评分比较,差异无统计学意义( P>0.05)。结论：COOK宫颈扩张球囊在足月妊娠促宫颈成熟引产中具有较好临床效果,不增加产妇和胎儿并发症,具有安全、有效的特点。
목적：：탐토COOK궁경확장구낭재족월임신촉궁경성숙인산중적림상효과급안전성。방법：회고성분석2011년9월지2014년10월엄주시화도구부유보건원수치적300례족월임신유인산지정잉부적림상자료,근거촉궁경성숙방식적불동분위연구조( COOK궁경확장구낭,173례)화대조조(지낙전렬동전,127례),비교량조촉궁경성숙정황、인산결국、신생인결국급인산과정차이。결과：치입혹용약후량조Bishop평분균교치료전제고(P<0.05),단량조지간차이무통계학의의(P>0.05)。연구조축궁소사용솔、인산성공솔、음도분면솔고우대조조,산후출혈량、부궁산솔저우대조조( P<0.05)；량조제일산정시간、궁경렬상발생솔、음도혈종솔、신생인체질량、신생인질식솔、신생인군박솔、신생인제1분종Apgar평분비교,차이무통계학의의( P>0.05)。결론：COOK궁경확장구낭재족월임신촉궁경성숙인산중구유교호림상효과,불증가산부화태인병발증,구유안전、유효적특점。
Objective:To investigate the clinical outcomes and safety of COOK cervical dilation balloon in promoting cervical ripening for induction labor in full-term pregnancies. Methods: A retrospective analysis of clinical data was conducted for 300 cases of full-term pregnancy indicated for induction labor at Huadu District Maternal and Children′s Hospital between September 2011 and October 2014. According to the methods of cervical ripening, the subjects were divided into study group ( COOK cervical dilatation balloon, n=173) and control group ( dinoprostone suppository, n=127) . The cervical ripening, outcomes of induction labor, neonatal outcome and induction process were compared between the both groups. Results: Compared with baseline, the two groups had increased Bishop scores after balloon placement or medication (P<0.05), but the difference between the two groups was not statistically significant ( P>0. 05 ) . The study group showed greater use of oxytocin, higher rates of induction success and vaginal delivery, but lower rates of postpartum hemorrhage and cesarean section than the control group ( P<0. 05 ) . There were no statistically significant differences in the duration of first-stage labor, cervical laceration, vaginal hematoma, newborn body mass, neonatal asphyxia, neonatal distress, and first-minute neonatal Apgar score between the two groups ( P>0.05) . Conclusion:COOK cervical dilation balloon is clinically favorable in promoting cervical ripening for induction labor in full-term pregnancy, and is safe and effective without increased maternal and fetal complications.