CAJ | 학술논문

目的：观察低频重复经颅磁刺激联合心理疗法治疗脑梗死后抑郁症的临床疗效。方法回顾性分析脑梗死后抑郁症患者120例，按照治疗方法不同分为观察组(采取低频重复经颅磁刺激联合心理疗法)和对照组(基础治疗加心理疗法加氟西汀口服)，以4周为1个疗程。观察治疗前后汉密尔顿抑郁量表(HAMD)、抑郁自评量表(SDS)、汉密尔顿焦虑量表(HAMA)、生活质量指数(Barthel)和安全性指标的变化。结果治疗组治疗后平均 HAMD、SDS和 HAMA评分较治疗前和对照组明显降低(P<0.05)；两组患者的Barthel积分比治疗前积分有明显升高(P<0.05)，但组间比较差异无统计学意义(P>0.05)。治疗组总有效率为90.0%，与对照组(78.3%)比较差异有统计学意义(P<0.05)。结论低频重复经颅磁刺激对脑梗死后抑郁患者的抑郁症状和神经功能均有明显的治疗作用，并对焦虑症状也有一定的改善作用。
목적：관찰저빈중복경로자자격연합심리요법치료뇌경사후억욱증적림상료효。방법회고성분석뇌경사후억욱증환자120례，안조치료방법불동분위관찰조(채취저빈중복경로자자격연합심리요법)화대조조(기출치료가심리요법가불서정구복)，이4주위1개료정。관찰치료전후한밀이돈억욱량표(HAMD)、억욱자평량표(SDS)、한밀이돈초필량표(HAMA)、생활질량지수(Barthel)화안전성지표적변화。결과치료조치료후평균 HAMD、SDS화 HAMA평분교치료전화대조조명현강저(P<0.05)；량조환자적Barthel적분비치료전적분유명현승고(P<0.05)，단조간비교차이무통계학의의(P>0.05)。치료조총유효솔위90.0%，여대조조(78.3%)비교차이유통계학의의(P<0.05)。결론저빈중복경로자자격대뇌경사후억욱환자적억욱증상화신경공능균유명현적치료작용，병대초필증상야유일정적개선작용。
Objective To investigate the effects of low frequency repetitive transcranial magnetic stimulation (rTMS)and psychother-apy in the treatment for patients with post stroke depression (PSD).Methods One hundred and twenty patients with PSD,accord-ing to the method of treatment,were divided into two groups:The control group treated with routine treatment plus psychotherapy,and the treatment group treated with low frequency rTMS plus psychotherapy for 4 weeks.The Hamilton Rating Scale for Depression (HAMD),self rating depression (SDS),Hamilton anxiety rating scale (HAMA),Barthel index(BI)and safety index were observed before and after treatment.Results After treatment,the scores of HAMD,SDS and HAMA in treatment group were significantly lower compared with the control group and before treatment(P<0.05).The BI were increased after treatment(P<0.05),but there was no differences between two groups(P>0.05).The total clinical effective rate was 90.0% in treatment group,which was higher than that in control group(78.3%,P<0.05).Conclusion Low frequency rTMS had significant therapeutic effect and could improve anxiety certain symptoms ment in patients with PSD.