广东医学
廣東醫學
엄동의학
Guangdong Medical Journal
2015年
17期
2621-2624
,共4页
王翦%赵义营%杨群英%赛克%柯超%张湘衡%陈银生%陈正和%林富华%GUO Cheng-cheng%ZHANG Ji%MU Yong-gao%CHEN Zhong-ping
王翦%趙義營%楊群英%賽剋%柯超%張湘衡%陳銀生%陳正和%林富華%GUO Cheng-cheng%ZHANG Ji%MU Yong-gao%CHEN Zhong-ping
왕전%조의영%양군영%새극%가초%장상형%진은생%진정화%림부화%GUO Cheng-cheng%ZHANG Ji%MU Yong-gao%CHEN Zhong-ping
脑肿瘤%综合治疗%儿童%外科治疗
腦腫瘤%綜閤治療%兒童%外科治療
뇌종류%종합치료%인동%외과치료
brain tumor%comprehensive treatment%children%surgical treatment
目的 分析接受手术治疗的儿童中枢神经系统肿瘤的病理特点、治疗模式及治疗效果,为合理规范的治疗及改善患儿预后提供参考.方法 对收治手术的219例中枢神经系统肿瘤患儿的临床资料进行回顾性分析.结果 219例儿童中枢神经系统肿瘤,以神经上皮组织来源肿瘤为主,其中主要是毛细胞型星形细胞瘤(25例)和WHOⅡ级星形细胞瘤(21例).在成年人较多见的脑膜瘤比较少,而在儿童多见的髓母细胞瘤、生殖细胞肿瘤在本组中分别占8.2%(18例)和11.0%(24例).在儿童高发的颅咽管瘤本组只占7.8%(17例).主要临床表现为头痛、呕吐、肢体瘫痪、步态不稳、抽搐、视力下降.219例术后接受单纯放疗31例(14%),单纯化疗16例(7%),放疗+化疗39例(17.8%).结论 毛细胞星形细胞瘤、生殖细胞肿瘤、星形细胞瘤、髓母细胞瘤、颅咽管瘤是儿童常见的中枢神经系统肿瘤类型.手术为主要治疗手段,术后予以放化疗可改善恶性肿瘤患儿预后.
目的 分析接受手術治療的兒童中樞神經繫統腫瘤的病理特點、治療模式及治療效果,為閤理規範的治療及改善患兒預後提供參攷.方法 對收治手術的219例中樞神經繫統腫瘤患兒的臨床資料進行迴顧性分析.結果 219例兒童中樞神經繫統腫瘤,以神經上皮組織來源腫瘤為主,其中主要是毛細胞型星形細胞瘤(25例)和WHOⅡ級星形細胞瘤(21例).在成年人較多見的腦膜瘤比較少,而在兒童多見的髓母細胞瘤、生殖細胞腫瘤在本組中分彆佔8.2%(18例)和11.0%(24例).在兒童高髮的顱嚥管瘤本組隻佔7.8%(17例).主要臨床錶現為頭痛、嘔吐、肢體癱瘓、步態不穩、抽搐、視力下降.219例術後接受單純放療31例(14%),單純化療16例(7%),放療+化療39例(17.8%).結論 毛細胞星形細胞瘤、生殖細胞腫瘤、星形細胞瘤、髓母細胞瘤、顱嚥管瘤是兒童常見的中樞神經繫統腫瘤類型.手術為主要治療手段,術後予以放化療可改善噁性腫瘤患兒預後.
목적 분석접수수술치료적인동중추신경계통종류적병리특점、치료모식급치료효과,위합리규범적치료급개선환인예후제공삼고.방법 대수치수술적219례중추신경계통종류환인적림상자료진행회고성분석.결과 219례인동중추신경계통종류,이신경상피조직래원종류위주,기중주요시모세포형성형세포류(25례)화WHOⅡ급성형세포류(21례).재성년인교다견적뇌막류비교소,이재인동다견적수모세포류、생식세포종류재본조중분별점8.2%(18례)화11.0%(24례).재인동고발적로인관류본조지점7.8%(17례).주요림상표현위두통、구토、지체탄탄、보태불은、추휵、시력하강.219례술후접수단순방료31례(14%),단순화료16례(7%),방료+화료39례(17.8%).결론 모세포성형세포류、생식세포종류、성형세포류、수모세포류、로인관류시인동상견적중추신경계통종류류형.수술위주요치료수단,술후여이방화료가개선악성종류환인예후.
Objective To analyze the pathological diagnosis,treatment strategies and clinical results of central nervous system (CNS) tumors in surgically treated children,and to provide data in setting treatment standard and impro-ving prognosis.Methods Clinical materials were retrospectively analyzed for the surgically treated pediatric patients with CNS tumors.Results There were 219 cases that received surgical treatment.Among these tumors the most common type was of neuroepithelial origin,including pilocytic astrocytomas in 25 cases,astrocytomas (WHO Grade Ⅱ) in 21cases.The common tumor type in adults,meningioma was fewer in our series,while common tumor types in children found in our series were medulloblastomas (18 cases,8.2%),germ cell tumors (24 cases,11.0%) and craniopharyngioma (17 ca-ses,7.8%) .The main clinical manifestations of craniopharyngioma were headache,vomiting,limb paralysis,gait insta-bility,convulsion,and impaired vision.After surgery,31 cases (14%) received radiotherapy only,16 cases (7%) re-ceived chemotherapy only,while 39 cases (17.8%) received radiochemotherapy.Conclusion Pilocytic astrocytoma,germ cell tumor,astrocytoma,medulloblastoma,craniopharyngioma are common types of CNS tumors in children.Surgery is the main treatment,radiotherapy and chemotherapy may improve prognosis for malignant tumor cases.
