辽宁医学院学报
遼寧醫學院學報
료녕의학원학보
Journal of Liaoning Medical University
2015年
5期
29-31
,共3页
肝硬化%胃蛋白酶原%胃泌素-17%Child-Paugh分级
肝硬化%胃蛋白酶原%胃泌素-17%Child-Paugh分級
간경화%위단백매원%위비소-17%Child-Paugh분급
liver cirrhosis%pepsinogen%gastric secrete element-17%the child-paugh classification
目的 探索肝硬化患者血清中胃蛋白酶原I (PGI)、 胃蛋白酶原Ⅱ (PGⅡ) 及胃泌素-17 (G-17) 的水平变化及临床意义. 方法 选取自2013年7月至2014年11月我院接收的肝硬化患者97例, 作为观察组; 另选取同期未患胃病的肝硬化患者92例, 作为对照组. 采用ELISA法分析肝硬化患者血清中PGI、 PGⅡ及G-17的水平变化. 结果 与对照组相比, 观察组患者血清中PGI、 PGⅡ和G-17水平明显高于对照组, 且差异具有统计学意义 ( P<0. 05 ). 另外, 与Child-Paugh A级相比, Child-Paugh C级患者血清中PGI、 PGⅡ和G-17的水平显著升高; Child-Paugh B级患者血清中PGI和G-17的水平明显升高, 差异具有统计学意义 (P<0. 05). 结论 肝硬化患者血清中PGI、 PGⅡ及G-17可以作为指标来表征胃部疾病, 且三个指标的水平与Child-Paugh 分级有一定的联系.
目的 探索肝硬化患者血清中胃蛋白酶原I (PGI)、 胃蛋白酶原Ⅱ (PGⅡ) 及胃泌素-17 (G-17) 的水平變化及臨床意義. 方法 選取自2013年7月至2014年11月我院接收的肝硬化患者97例, 作為觀察組; 另選取同期未患胃病的肝硬化患者92例, 作為對照組. 採用ELISA法分析肝硬化患者血清中PGI、 PGⅡ及G-17的水平變化. 結果 與對照組相比, 觀察組患者血清中PGI、 PGⅡ和G-17水平明顯高于對照組, 且差異具有統計學意義 ( P<0. 05 ). 另外, 與Child-Paugh A級相比, Child-Paugh C級患者血清中PGI、 PGⅡ和G-17的水平顯著升高; Child-Paugh B級患者血清中PGI和G-17的水平明顯升高, 差異具有統計學意義 (P<0. 05). 結論 肝硬化患者血清中PGI、 PGⅡ及G-17可以作為指標來錶徵胃部疾病, 且三箇指標的水平與Child-Paugh 分級有一定的聯繫.
목적 탐색간경화환자혈청중위단백매원I (PGI)、 위단백매원Ⅱ (PGⅡ) 급위비소-17 (G-17) 적수평변화급림상의의. 방법 선취자2013년7월지2014년11월아원접수적간경화환자97례, 작위관찰조; 령선취동기미환위병적간경화환자92례, 작위대조조. 채용ELISA법분석간경화환자혈청중PGI、 PGⅡ급G-17적수평변화. 결과 여대조조상비, 관찰조환자혈청중PGI、 PGⅡ화G-17수평명현고우대조조, 차차이구유통계학의의 ( P<0. 05 ). 령외, 여Child-Paugh A급상비, Child-Paugh C급환자혈청중PGI、 PGⅡ화G-17적수평현저승고; Child-Paugh B급환자혈청중PGI화G-17적수평명현승고, 차이구유통계학의의 (P<0. 05). 결론 간경화환자혈청중PGI、 PGⅡ급G-17가이작위지표래표정위부질병, 차삼개지표적수평여Child-Paugh 분급유일정적련계.
Objective To explore the content change of pepsinogenI ( PGI) , pepsinogenⅡ ( PGⅡ) and gastric secrete ele-ment-17 (G-17) in patients with cirrhosis serum and its clinical significance. Methods 97 cases of patients with liver cirrhosis in our hospital from July 2013 to November 2014 were selected as the observation group and 92 cases of patients with liver cirrhosis but with no gastrosis at the same period were selected as the control group. The serum content of in PGI, PGⅡand G-17 were detected by ELISA. Results Compared with the control group, the PGI, PGⅡand G-17 serum levels in the observation group were signifi-cantly high and the difference was statistically significant (P<0. 05). In addition, compared with the Child-Paugh a-class, the con-tent of PGI, PGⅡand G-17 in Child-Paugh c-class patients′ serum significantly increased, and the levels of PGIand G-17 in Child-Paugh B patients' serum increased significantly, with statistically significant difference (P<0. 05). Conclusion The PGI, PGⅡ and G-17 in patients with cirrhosis serum can be used as an index to characterize the stomach disease, and the content of the three indicators proves to be related with the Child-Paugh grading.
