中外医疗
中外醫療
중외의료
China Foreign Medical Treatment
2015年
27期
113-114
,共2页
榄香烯%化疗%肺癌%增效减毒
欖香烯%化療%肺癌%增效減毒
람향희%화료%폐암%증효감독
Elemene%Chemotherapy%Lung cancer%Toxicity%Reducing
目的 探讨榄香烯对肺癌化疗的增效减少不良反应. 方法 将随机选取的该院于2011 年1月-2015年5月收治的120例非小细胞肺癌患者随机分为两组,各60例.均给予常规化疗治疗,观察组在此基础上给予榄香烯治疗,比较两组近期疗效及毒副反应. 结果 观察组RR为65.00%,对照组为38.33%,观察组近期疗效明显高于对照组P<0.01;观察组治疗后FACT-L生存质量评分明显优于对照组P<0.01; 观察组胃肠道反应、 白细胞减少及血小板减少发生率明显低于对照组P<0.05. 结论 榄香烯对肺癌化疗增效作用显著,且能减少化疗药物的毒副反应.
目的 探討欖香烯對肺癌化療的增效減少不良反應. 方法 將隨機選取的該院于2011 年1月-2015年5月收治的120例非小細胞肺癌患者隨機分為兩組,各60例.均給予常規化療治療,觀察組在此基礎上給予欖香烯治療,比較兩組近期療效及毒副反應. 結果 觀察組RR為65.00%,對照組為38.33%,觀察組近期療效明顯高于對照組P<0.01;觀察組治療後FACT-L生存質量評分明顯優于對照組P<0.01; 觀察組胃腸道反應、 白細胞減少及血小闆減少髮生率明顯低于對照組P<0.05. 結論 欖香烯對肺癌化療增效作用顯著,且能減少化療藥物的毒副反應.
목적 탐토람향희대폐암화료적증효감소불량반응. 방법 장수궤선취적해원우2011 년1월-2015년5월수치적120례비소세포폐암환자수궤분위량조,각60례.균급여상규화료치료,관찰조재차기출상급여람향희치료,비교량조근기료효급독부반응. 결과 관찰조RR위65.00%,대조조위38.33%,관찰조근기료효명현고우대조조P<0.01;관찰조치료후FACT-L생존질량평분명현우우대조조P<0.01; 관찰조위장도반응、 백세포감소급혈소판감소발생솔명현저우대조조P<0.05. 결론 람향희대폐암화료증효작용현저,차능감소화료약물적독부반응.
Objective To investigate effect of reducing toxicity of elemene for lung cancer chemotherapy. Methods 120 patients from 2011 January to 2015 May with non-small cell lung cancer were randomly divided into two groups, 60 cases in each group. Were given conventional chemotherapy for treatment, based on this, observation group were given elemene treatment, short-term effect and toxicity of two groups were compared. Results RR of observation group was 65.00%, control group was 38.33%, short-term efficacy of observation group was significantly higher than control group P<0.01; FACT-L QoL after treatment of observation group was significantly better than control group, P<0.01;GI reactions, leukopenia and thrombocytopenia of observation group were significantly lower than control group, P<0.05. Conclusion Effect of reducing toxicity of elemene for lung cancer chemotherapy is significant, can reduce the toxicity of chemotherapy drugs.
