广东医学
廣東醫學
엄동의학
Guangdong Medical Journal
2015年
17期
2731-2733
,共3页
韩嘉宁%邓宇虹%熊龙根%李国强
韓嘉寧%鄧宇虹%熊龍根%李國彊
한가저%산우홍%웅룡근%리국강
植物甾醇%高脂血症%他汀%血脂谱
植物甾醇%高脂血癥%他汀%血脂譜
식물치순%고지혈증%타정%혈지보
phytosterols%hyperlipidemia%statin therapy%lipid profile
目的 探讨植物甾醇膳食干预对高胆固醇血症的疗效,为高脂血症治疗提供新的手段.方法 随机抽取门诊经他汀治疗2个月未达标的高脂血症患者,分别给予不同剂量植物甾醇,观察干预前及1、3个月后患者的总胆固醇、三酰甘油、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇的变化情况.结果 中剂量组膳食干预3个月及高剂量组膳食干预1个月后患者血清总胆固醇及低密度脂蛋白胆固醇水平显著降低.结论 植物甾醇膳食干预有助于改善他汀治疗未达标患者的血脂谱.
目的 探討植物甾醇膳食榦預對高膽固醇血癥的療效,為高脂血癥治療提供新的手段.方法 隨機抽取門診經他汀治療2箇月未達標的高脂血癥患者,分彆給予不同劑量植物甾醇,觀察榦預前及1、3箇月後患者的總膽固醇、三酰甘油、高密度脂蛋白膽固醇和低密度脂蛋白膽固醇的變化情況.結果 中劑量組膳食榦預3箇月及高劑量組膳食榦預1箇月後患者血清總膽固醇及低密度脂蛋白膽固醇水平顯著降低.結論 植物甾醇膳食榦預有助于改善他汀治療未達標患者的血脂譜.
목적 탐토식물치순선식간예대고담고순혈증적료효,위고지혈증치료제공신적수단.방법 수궤추취문진경타정치료2개월미체표적고지혈증환자,분별급여불동제량식물치순,관찰간예전급1、3개월후환자적총담고순、삼선감유、고밀도지단백담고순화저밀도지단백담고순적변화정황.결과 중제량조선식간예3개월급고제량조선식간예1개월후환자혈청총담고순급저밀도지단백담고순수평현저강저.결론 식물치순선식간예유조우개선타정치료미체표환자적혈지보.
Objective To investigate the efficacy of dietary intervention with phytosterols for hypercholesterol-emia,providing new tools for the treatment of hyperlipidemia.Methods Patients with hyperlipidemia who did not meet the treatment goal after two months of out-patient statin therapy were randomly selected.Patients were given different do-ses of phytosterols.Changes in total cholesterol,triglycerides,high density lipoprotein-cholesterol (HDL-cholesterol) and low density lipoprotein-cholesterol (LDL-cholesterol) before the intervention,1 and 3 months after were observed.Results Serum total cholesterol and LDL-cholesterol levels were significantly reduced in the intermediate dose group after three months of dietary intervention and in the high-dose group after a month of dietary intervention.Conclusion Phytos-terols dietary intervention helps improve the patient′s lipid profile whose treatment goals were not met after statin therapy.
