辽宁医学院学报
遼寧醫學院學報
료녕의학원학보
Journal of Liaoning Medical University
2015年
5期
49-51
,共3页
高通量血液透析%维持性血液透析%钙磷代谢
高通量血液透析%維持性血液透析%鈣燐代謝
고통량혈액투석%유지성혈액투석%개린대사
high flux hemodialysis%maintenance hemodialysis%calcium and phosphorus metabolism
目的 探讨高、 低通量血液透析对维持性血液透析患者钙磷代谢、 甲状旁腺激素的影响. 方法 选取在我院接受血液透析治疗的维持性血液透析患者118例, 随机分为A组和B组各59例. A组接受常规的低通量血液透析, B组接受高通量血液透析. 对比两组患者血透前和血透1个月后的血肌酐、 尿素氮、 甲状旁腺素、 血钙、 血磷水平的变化情况. 结果 两组患者血透前后的血肌酐、 尿素氮水平及其差值的对比, 差异均没有统计学意义 (均P>0. 05 ); B组血透后的甲状旁腺素水平为 (159. 74±114. 83) μg/L, 差值为 (319. 36±20. 08) μg/L, 显著低于A组 (P<0. 05); B组血液透析后的血钙水平为 (2. 32±0. 20) mmol/L, 血磷水平差值为 (0. 26±0. 07) mmol/L, 显著高于A组, 而血磷水平为 (2. 19±0. 59) mmol/L, 血钙水平差值为 (-0. 13±0. 03) mmol/L, 显著低于A组 (均P<0. 05). 结论 高通量血液透析能通过降低血磷有效的纠正维持性血液透析患者钙磷代谢紊乱的状态, 降低甲状旁腺激素水平, 有助于患者生活质量的提高和预后的改善.
目的 探討高、 低通量血液透析對維持性血液透析患者鈣燐代謝、 甲狀徬腺激素的影響. 方法 選取在我院接受血液透析治療的維持性血液透析患者118例, 隨機分為A組和B組各59例. A組接受常規的低通量血液透析, B組接受高通量血液透析. 對比兩組患者血透前和血透1箇月後的血肌酐、 尿素氮、 甲狀徬腺素、 血鈣、 血燐水平的變化情況. 結果 兩組患者血透前後的血肌酐、 尿素氮水平及其差值的對比, 差異均沒有統計學意義 (均P>0. 05 ); B組血透後的甲狀徬腺素水平為 (159. 74±114. 83) μg/L, 差值為 (319. 36±20. 08) μg/L, 顯著低于A組 (P<0. 05); B組血液透析後的血鈣水平為 (2. 32±0. 20) mmol/L, 血燐水平差值為 (0. 26±0. 07) mmol/L, 顯著高于A組, 而血燐水平為 (2. 19±0. 59) mmol/L, 血鈣水平差值為 (-0. 13±0. 03) mmol/L, 顯著低于A組 (均P<0. 05). 結論 高通量血液透析能通過降低血燐有效的糾正維持性血液透析患者鈣燐代謝紊亂的狀態, 降低甲狀徬腺激素水平, 有助于患者生活質量的提高和預後的改善.
목적 탐토고、 저통량혈액투석대유지성혈액투석환자개린대사、 갑상방선격소적영향. 방법 선취재아원접수혈액투석치료적유지성혈액투석환자118례, 수궤분위A조화B조각59례. A조접수상규적저통량혈액투석, B조접수고통량혈액투석. 대비량조환자혈투전화혈투1개월후적혈기항、 뇨소담、 갑상방선소、 혈개、 혈린수평적변화정황. 결과 량조환자혈투전후적혈기항、 뇨소담수평급기차치적대비, 차이균몰유통계학의의 (균P>0. 05 ); B조혈투후적갑상방선소수평위 (159. 74±114. 83) μg/L, 차치위 (319. 36±20. 08) μg/L, 현저저우A조 (P<0. 05); B조혈액투석후적혈개수평위 (2. 32±0. 20) mmol/L, 혈린수평차치위 (0. 26±0. 07) mmol/L, 현저고우A조, 이혈린수평위 (2. 19±0. 59) mmol/L, 혈개수평차치위 (-0. 13±0. 03) mmol/L, 현저저우A조 (균P<0. 05). 결론 고통량혈액투석능통과강저혈린유효적규정유지성혈액투석환자개린대사문란적상태, 강저갑상방선격소수평, 유조우환자생활질량적제고화예후적개선.
Objective To explore the effect of high and low flux dialysis on calcium and phosphate metabolism and parathyroid hormone in maintained hemodialysis patients. Methods 118 patients with maintenance hemodialysis who received hemodialysis in our hospital were randomly divided into group A and group B with 59 cases in each group. Patients in group A received conventional low flux hemodialysis, and patients in group B received high flux hemodialysis. The level change of serum creatinine, urea nitrogen, para-thyroid hormone, blood calcium and phosphorus of both groups before and one month after hemodialysis were compared. Results The differences in the levels of serum creatinine and urea nitrogen of the two groups before and after hemodialysis were not statistically sig-nificant (all P>0. 05). The parathyroid hormone level of group B was (159. 74±114. 83) μg/L, and its difference was (319. 36± 20. 08) μg/L , which was significantly lower than that of group A (P<0. 05). The serum calcium level of group B after hemodialysis was (2. 32±0. 20) mmol/L, and the difference of serum phosphorus level was (0. 26±0. 07) mmol/L, which was significantly higher than that of group A. The serum phosphorus level of group B after hemodialysis was (2. 19±0. 59) mmol/L, and the difference of ser-um calcium level was (-0. 13±0. 03) mmol/L, which was significantly lower than that of group A (all P<0. 05). Conclusion High flux hemodialysis can effectively correct the disorder of calcium and phosphorus metabolism in maintenance hemodialysis patients by re-ducing the level of serum phosphorus, and reduce the level of parathyroid hormone. It helps to promote the quality of life of the patients and improve the prognosis.
