中国全科医学
中國全科醫學
중국전과의학
Chinese General Practice
2015年
31期
3868-3871
,共4页
周志航%郭湄%扈腾腾%祝伟娟%张国辉%张英杰
週誌航%郭湄%扈騰騰%祝偉娟%張國輝%張英傑
주지항%곽미%호등등%축위연%장국휘%장영걸
活血通痹汤%运动疗法%骨关节炎, 膝%治疗结果
活血通痺湯%運動療法%骨關節炎, 膝%治療結果
활혈통비탕%운동요법%골관절염, 슬%치료결과
Huoxue tongbi decoction%Exercise therapy%Knee osteoarthritis%Treatment outcome
目的：探讨活血通痹汤联合运动疗法治疗早中期膝关节骨性关节炎( KOA)的近期疗效。方法选取2010年3月—2014年3月在山东省青州市中医院骨伤科、康复科门诊与住院的早中期KOA患者126例,采用随机数字表法分为治疗组60例和对照组66例。两组均进行膝关节腔内注射玻璃酸钠。在此基础上,治疗组采用活血通痹汤联合阶段性运动疗法,对照组口服盐酸氨基葡萄糖片。比较两组治疗前和治疗后6周的临床疗效、视觉模拟评分法(VAS)评分、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分。结果对照组中,临床控制32例(占48．5%),显效13例(占19．7%),有效12例(占18．2%),无效9例(占13．6%)；治疗组中,临床控制40例(占66．7%),显效14例(占23．3%),有效4例(占6．7%),无效2例(占3．3%)。两组患者的临床疗效比较,差异有统计学意义(u=-2．32, P<0．05)。两组VAS评分比较,治疗前差异无统计学意义(P>0．05)；治疗后6周差异有统计学意义(P<0．05)。两组僵硬、疼痛、日常生活受限各项评分及WOMAC总分比较,治疗前差异均无统计学意义(P>0．05)；治疗后6周差异均有统计学意义(P<0．05)。结论活血通痹汤联合阶段性运动疗法在早中期KOA患者的治疗中近期疗效显著,安全性佳。
目的：探討活血通痺湯聯閤運動療法治療早中期膝關節骨性關節炎( KOA)的近期療效。方法選取2010年3月—2014年3月在山東省青州市中醫院骨傷科、康複科門診與住院的早中期KOA患者126例,採用隨機數字錶法分為治療組60例和對照組66例。兩組均進行膝關節腔內註射玻璃痠鈉。在此基礎上,治療組採用活血通痺湯聯閤階段性運動療法,對照組口服鹽痠氨基葡萄糖片。比較兩組治療前和治療後6週的臨床療效、視覺模擬評分法(VAS)評分、西安大略和麥剋馬斯特大學骨關節炎指數(WOMAC)評分。結果對照組中,臨床控製32例(佔48．5%),顯效13例(佔19．7%),有效12例(佔18．2%),無效9例(佔13．6%)；治療組中,臨床控製40例(佔66．7%),顯效14例(佔23．3%),有效4例(佔6．7%),無效2例(佔3．3%)。兩組患者的臨床療效比較,差異有統計學意義(u=-2．32, P<0．05)。兩組VAS評分比較,治療前差異無統計學意義(P>0．05)；治療後6週差異有統計學意義(P<0．05)。兩組僵硬、疼痛、日常生活受限各項評分及WOMAC總分比較,治療前差異均無統計學意義(P>0．05)；治療後6週差異均有統計學意義(P<0．05)。結論活血通痺湯聯閤階段性運動療法在早中期KOA患者的治療中近期療效顯著,安全性佳。
목적：탐토활혈통비탕연합운동요법치료조중기슬관절골성관절염( KOA)적근기료효。방법선취2010년3월—2014년3월재산동성청주시중의원골상과、강복과문진여주원적조중기KOA환자126례,채용수궤수자표법분위치료조60례화대조조66례。량조균진행슬관절강내주사파리산납。재차기출상,치료조채용활혈통비탕연합계단성운동요법,대조조구복염산안기포도당편。비교량조치료전화치료후6주적림상료효、시각모의평분법(VAS)평분、서안대략화맥극마사특대학골관절염지수(WOMAC)평분。결과대조조중,림상공제32례(점48．5%),현효13례(점19．7%),유효12례(점18．2%),무효9례(점13．6%)；치료조중,림상공제40례(점66．7%),현효14례(점23．3%),유효4례(점6．7%),무효2례(점3．3%)。량조환자적림상료효비교,차이유통계학의의(u=-2．32, P<0．05)。량조VAS평분비교,치료전차이무통계학의의(P>0．05)；치료후6주차이유통계학의의(P<0．05)。량조강경、동통、일상생활수한각항평분급WOMAC총분비교,치료전차이균무통계학의의(P>0．05)；치료후6주차이균유통계학의의(P<0．05)。결론활혈통비탕연합계단성운동요법재조중기KOA환자적치료중근기료효현저,안전성가。
Objective To observe short-term effect of huoxue tongbi decoction combined with exercise therapy on knee osteoarthritis ( KOA) of early and middle stage. Methods We enrolled 126 KOA patients who were hospitalized in the Department of Orthopaedics and Traumatology and the Department of Rehabilitation of Qingzhou Hospital of Traditional Chinese Medicine in Shandong Province from March 2010 to March 2014. Using random number table method, the patients were divided into treatment group ( n =60 ) and control group ( n =66 ) . The two groups were administrated with sodium hyaluronate by injection into knee articular cavity, on the basis of which treatment group was administrated with huoxue tongbi decoction combined with multi - stage exercise therapy and control group was orally administrated with glucosamine hydrochloride tablets. Comparison was made in clinical efficacy, VAS and WOMAC between the two groups before treatment and six weeks after treatment. Results In control group, the disease of 32 ( 48. 5%) subjects were clinically controlled, 13 ( 19. 7%) subjects saw obvious efficacy, 12 (18. 2%) subjects saw efficacy, and 9 (13. 6%) subjects saw no efficacy; in treatment group, the disease of 40 (66. 7%) subjects were clinically controlled, 14 (23. 3%) subjects saw obvious efficacy, 4 (6. 7%) subjects saw efficacy, and 2 ( 3. 3%) subjects saw no efficacy. The comparison of clinical efficacy between the two groups showed significant difference (u = -2. 32, P <0. 05) . The two groups were not significantly different (P >0. 05) in VAS before treatment and were significantly different ( P <0. 05 ) in VAS six weeks after treatment. The two groups were not significantly different (P>0. 05) before treatment and were significantly different (P<0. 05) six weeks after treatment in stiffness, pain, scores of daily life restrictions and the total score of WOMAC. Conclusion Huoxue tongbi decoction combined with multi-stage exercise therapy has remarkable short-term efficacy in the treatment of knee osteoarthritis of early and middle stage and has good safety.
