实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
2015年
9期
71-73
,共3页
徐建萍%王何刚%何旺%王红民
徐建萍%王何剛%何旺%王紅民
서건평%왕하강%하왕%왕홍민
肺疾病,慢性阻塞性%代谢综合征%颈动脉内膜中膜厚度
肺疾病,慢性阻塞性%代謝綜閤徵%頸動脈內膜中膜厚度
폐질병,만성조새성%대사종합정%경동맥내막중막후도
Pulmonary disease,chronic obstructive%Metabolic syndrome%Carotid intima - media thickness
目的:探讨慢性阻塞性肺疾病(COPD)患者代谢综合征与颈动脉内膜中膜厚度( IMT)的相关性。方法选取2013—2014年就诊于西安市第一医院的60例 COPD 患者作为 COPD 组,另选取同期在西安市第一医院体检中心进行体检的无 COPD 病史的健康者60例作为对照组。所有受试者在入组时记录人口学信息及既往病史,采集空腹静脉血检测空腹血糖(FPG)、三酰甘油(TG)及高密度脂蛋白胆固醇(HDL - C)水平;采用颈动脉超声检查仪检查颈动脉 IMT;对颈动脉 IMT 的相关因素进行多元逐步线性回归分析。结果 COPD 组患者代谢综合征发生率为51.7%,高于对照组的30.0%(P <0.05);COPD 组患者颈动脉 IMT 为(1.07±0.25)mm,高于对照组的(0.86±0.18)mm (P <0.05)。多元线性回归分析结果显示,COPD 发生率(β=0.24,P =0.00)、年龄(β=0.18,P =0.01)及 BMI (β=0.18,P =0.03)与颈动脉 IMT 呈线性相关,而代谢综合征发生率与颈动脉 IMT 无直线相关性(β=0.10,P =0.26)。结论 COPD 患者代谢综合征发生率及颈动脉 IMT 明显增高,但代谢综合征与颈动脉 IMT 无直线相关性。
目的:探討慢性阻塞性肺疾病(COPD)患者代謝綜閤徵與頸動脈內膜中膜厚度( IMT)的相關性。方法選取2013—2014年就診于西安市第一醫院的60例 COPD 患者作為 COPD 組,另選取同期在西安市第一醫院體檢中心進行體檢的無 COPD 病史的健康者60例作為對照組。所有受試者在入組時記錄人口學信息及既往病史,採集空腹靜脈血檢測空腹血糖(FPG)、三酰甘油(TG)及高密度脂蛋白膽固醇(HDL - C)水平;採用頸動脈超聲檢查儀檢查頸動脈 IMT;對頸動脈 IMT 的相關因素進行多元逐步線性迴歸分析。結果 COPD 組患者代謝綜閤徵髮生率為51.7%,高于對照組的30.0%(P <0.05);COPD 組患者頸動脈 IMT 為(1.07±0.25)mm,高于對照組的(0.86±0.18)mm (P <0.05)。多元線性迴歸分析結果顯示,COPD 髮生率(β=0.24,P =0.00)、年齡(β=0.18,P =0.01)及 BMI (β=0.18,P =0.03)與頸動脈 IMT 呈線性相關,而代謝綜閤徵髮生率與頸動脈 IMT 無直線相關性(β=0.10,P =0.26)。結論 COPD 患者代謝綜閤徵髮生率及頸動脈 IMT 明顯增高,但代謝綜閤徵與頸動脈 IMT 無直線相關性。
목적:탐토만성조새성폐질병(COPD)환자대사종합정여경동맥내막중막후도( IMT)적상관성。방법선취2013—2014년취진우서안시제일의원적60례 COPD 환자작위 COPD 조,령선취동기재서안시제일의원체검중심진행체검적무 COPD 병사적건강자60례작위대조조。소유수시자재입조시기록인구학신식급기왕병사,채집공복정맥혈검측공복혈당(FPG)、삼선감유(TG)급고밀도지단백담고순(HDL - C)수평;채용경동맥초성검사의검사경동맥 IMT;대경동맥 IMT 적상관인소진행다원축보선성회귀분석。결과 COPD 조환자대사종합정발생솔위51.7%,고우대조조적30.0%(P <0.05);COPD 조환자경동맥 IMT 위(1.07±0.25)mm,고우대조조적(0.86±0.18)mm (P <0.05)。다원선성회귀분석결과현시,COPD 발생솔(β=0.24,P =0.00)、년령(β=0.18,P =0.01)급 BMI (β=0.18,P =0.03)여경동맥 IMT 정선성상관,이대사종합정발생솔여경동맥 IMT 무직선상관성(β=0.10,P =0.26)。결론 COPD 환자대사종합정발생솔급경동맥 IMT 명현증고,단대사종합정여경동맥 IMT 무직선상관성。
Objective To investigate the correlation between metabolic syndrome and carotid intima - media thickness (CIMT)in patients with chronic obstructive pulmonary disease(COPD). Methods A total of 60 patients with COPD were selected as case group in the First Hospital of Xi'an from 2013 to 2014,and a total of 60 healthy people without history of COPD were selected as control group. Demographic information and past medical history were recorded,FPG,TG and HDL - C were detected,carotid artery ultrasound was used to examine CIMT,and multiple stepwise linear regression analysis was used to analyze the influencing factors of CIMT. Results The incidence of metabolic syndrome of case group was 51. 7% ,was statistically significantly higher than that of control group of 30. 0% (P < 0. 05). The CIMT of case group was(1. 07 ± 0. 25) mm,was statistically significantly higher than that of control group of(0. 86 ± 0. 18)mm(P < 0. 05). Multiple stepwise linear regression analysis showed that,incidence of COPD(β = 0. 24,P = 0. 00),age(β = 0. 18,P = 0. 01),BMI(β = 0. 18,P= 0. 03)was linearly correlated with CIMT,while incidence of metabolic syndrome was not linearly correlated with CIMT(β =0. 10,P = 0. 26). Conclusion The incidence of metabolic syndrome and CIMT of patients with COPD were significantly elevated,but there was no linearly correlation between metabolic syndrome and CIMT.