实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
2015年
9期
62-64
,共3页
孙薇%杨建波%徐金凤%张倩%邹全%孟新玲
孫薇%楊建波%徐金鳳%張倩%鄒全%孟新玲
손미%양건파%서금봉%장천%추전%맹신령
痴呆,血管性%丁苯酞软胶囊%高压氧%老年人
癡呆,血管性%丁苯酞軟膠囊%高壓氧%老年人
치태,혈관성%정분태연효낭%고압양%노년인
Dementia,vascular%Butylphthalide soft capsules%Hyperbaric oxygenation%Aged
目的：观察丁苯酞软胶囊联合高压氧治疗老年血管性痴呆的临床疗效。方法选择2013年2月—2014年2月新疆医科大学附属中医医院收治的老年血管性痴呆患者60例，随机分为对照组和观察组，各30例。对照组患者在常规药物治疗基础上应用丁苯酞软胶囊治疗；观察组患者在对照组基础上联合高压氧治疗，两组患者均连续治疗24 d。比较两组患者临床疗效及治疗前后简易精神状态检查量表（MMSE）评分，并观察治疗期间不良反应发生情况。结果观察组患者临床疗效优于对照组（ P <0.05）。两组患者治疗前 MMSE 评分比较，差异无统计学意义（ P >0.05）；治疗后观察组患者 MMSE 评分高于对照组（P <0.05）。观察组患者不良反应发生率为6.7%，低于对照组的30.0%（P <0.05）。结论丁苯酞软胶囊联合高压氧治疗老年血管性痴呆的临床疗效确切，能有效改善患者认知功能，且安全性较高。
目的：觀察丁苯酞軟膠囊聯閤高壓氧治療老年血管性癡呆的臨床療效。方法選擇2013年2月—2014年2月新疆醫科大學附屬中醫醫院收治的老年血管性癡呆患者60例，隨機分為對照組和觀察組，各30例。對照組患者在常規藥物治療基礎上應用丁苯酞軟膠囊治療；觀察組患者在對照組基礎上聯閤高壓氧治療，兩組患者均連續治療24 d。比較兩組患者臨床療效及治療前後簡易精神狀態檢查量錶（MMSE）評分，併觀察治療期間不良反應髮生情況。結果觀察組患者臨床療效優于對照組（ P <0.05）。兩組患者治療前 MMSE 評分比較，差異無統計學意義（ P >0.05）；治療後觀察組患者 MMSE 評分高于對照組（P <0.05）。觀察組患者不良反應髮生率為6.7%，低于對照組的30.0%（P <0.05）。結論丁苯酞軟膠囊聯閤高壓氧治療老年血管性癡呆的臨床療效確切，能有效改善患者認知功能，且安全性較高。
목적：관찰정분태연효낭연합고압양치료노년혈관성치태적림상료효。방법선택2013년2월—2014년2월신강의과대학부속중의의원수치적노년혈관성치태환자60례，수궤분위대조조화관찰조，각30례。대조조환자재상규약물치료기출상응용정분태연효낭치료；관찰조환자재대조조기출상연합고압양치료，량조환자균련속치료24 d。비교량조환자림상료효급치료전후간역정신상태검사량표（MMSE）평분，병관찰치료기간불량반응발생정황。결과관찰조환자림상료효우우대조조（ P <0.05）。량조환자치료전 MMSE 평분비교，차이무통계학의의（ P >0.05）；치료후관찰조환자 MMSE 평분고우대조조（P <0.05）。관찰조환자불량반응발생솔위6.7%，저우대조조적30.0%（P <0.05）。결론정분태연효낭연합고압양치료노년혈관성치태적림상료효학절，능유효개선환자인지공능，차안전성교고。
Objective To observe the clinical effect of butylphthalide soft capsules combined with hyperbaric oxygenation on senile vascular dementia. Methods A total of 60 patients with senile vascular dementia were selected in the Affiliated Traditional Chinese Medicine Hospital of Xinjiang Medical University from February 2013 to February 2014,and they were randomly divided into control group and observation group,each of 30 cases. Based on routine drug treatment,patients of control group were given extra butylphthalide soft capsules,while patients of observation group were given extra butylphthalide soft capsules combined with hyperbaric oxygenation,both groups treated for 24 days. MMSE score before and after treatment,clinical effect were compared between the two groups,and incidence of adverse reactions was observed during treatment. Results The clinical effect of observation group was statistically significantly better than that of control group( P < 0. 05). No statistically significant difference of MMSE score was found between the two groups before treatment( P > 0. 05),while MMSE score of observation group was statistically significantly higher than that of control group(P < 0. 05). The incidence of observation group was 6. 7% ,was statistically significantly lower than that of control group of 30. 0% (P < 0. 05). Conclusion Butylphthalide soft capsules combined with hyperbaric oxygenation has certain clinical effect on senile vascular dementia,which can effectively improve the cognitive function with high safety.
